Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

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Country Product Indication Sponsor Date
Purified type II collagen Juvenile rheumatoid arthritis AutoImmune, Inc.;128 Spring Street;Lexington, Massachusetts, 02421 February 9, 1995
Chondroitinase Patients undergoing vitrectomy Bausch & Lomb Pharmaceuticals, Inc.;8500 Hidden River Pkwy.;Tampa, Florida, 33637 February 9, 1995
Aminocaproic acid For the topical treatment of traumatic hyphema of the eye Eastern Virginia Medical School;Department of Ophthalomology, 880 Kempsville Road, Suite 2500;Norfolk, Virginia, 23502 January 6, 1995
Human immunodeficiency virus immune globulin HIV-infected pediatric patients NABI;5800 Park of Commerce Blvd., NW;Boca Raton, Florida, 33487 January 4, 1995
Coumarin Renal cancer Drossapharm LTD;4002 Basel; December 22, 1994
Somatostatin Bleeding esophageal varices Eumedica Pharmaceuticals A.G. (Schweiz);Arnold Bocklin-Strasse 1, CH-4051;BASEL December 22, 1994
Orgotein for injection Amyotrophic lateral sclerosis Oxis International, Inc.;6040 N. Cutter Circle, Suite 317;Portland, Oregon, 97217 December 22, 1994
Recombinant methionyl brain-derived neurotrophic factor Amyotrophic lateral sclerosis Amgen, Inc.;One Amgen Center Dr., M/S: 17-2-B;Thousand Oaks, California, 91320 November 28, 1994
Dimethyl sulfoxide Increased intracranial pressure in patients with severe, closed-head injury, also known as traumatic brain coma, for whom no other effective treatment is available Abela Pharmaceuticals, Inc.;21581 Midcrest Drive;Lake Forest, California, 92630 November 22, 1994
Soluble recombinant human complement receptor type 1 Prevention or reduction of adult respiratory distress syndrome T Cell Sciences, Inc.;119 Fourth Avenue;Needham Heights, Massachusetts, 02194 November 21, 1994
Sodium dichloroacetate Lactic acidosis in patients with severe malaria Stacpoole, Peter W. M.D., Ph.D.;University of Florida, P.O. Box 100277;Gainesville, Florida, 32610 November 10, 1994
Dapsone Prophylaxis of toxoplasmosis in severely immunocompromised patients with CD4 counts below 100 Jacobus Pharmaceutical Company, Inc.;37 Cleveland Lane, P.O. Box 5290;Princeton, New Jersey, 08540 November 7, 1994
Buprenorphine in combination with naloxone Opiate addiction in opiate users Indivior, Inc.;10710 Midlothian Turnpike, Suite 430;Richmond, Virginia, 23235 October 27, 1994
Melanoma cell vaccine Invasive melanoma CancerVax Corporation;2110 Rutherford Road;Carlsbad, California, 92008 October 13, 1994
Tobramycin for inhalation Cystic fibrosis Novartis Pharmaceuticals Corp;Drug Regulatory Affairs, One Health Plaza;East Hanover, New Jersey, 07936 October 13, 1994
Recombinant human luteinizing hormone For use in association with recombinant human follicle stimulating hormone for the treatment of women with chronic anovulation due to hypogonadotropic hypogonadism EMD Serono, Inc.;One Technology Place;Rockland, Massachusetts, 02370 October 7, 1994
Coagulation Factor IX (recombinant) Hemophilia B Genetics Institute, Inc.;87 Cambridge Park Drive;Cambridge, Massachusetts, 02140 October 3, 1994
Baclofen Spasticity associated with cerebral palsy Medtronic, Inc.;800 53rd Avenue N.E., P.O. 1250;Minneapolis, Minnesota, 55440 September 26, 1994
Monoclonal Ab(murine) anti-idiotype melanoma-associated antigen Invasive cutaneous melanoma IDEC Pharmaceuticals Corporation;3030 Callan Road;San Diego, California, 92121 September 19, 1994
Neurotrophin-1 Motor neuron disease/amyotrophic lateral sclerosis Ericsson, Arthur Dale, M.D.;Institute of Biologic Research, 6560 Fannin, Suite 720;Houston, Texas, 77030 September 13, 1994
Aminosidine Leishmaniasis Kanyok, Thomas P. Pharm.D.;University of Illinois at Chicago College of Pharm, 833 South Wood Street (m/c886) Rm. 176;Chicago, Illinois, 60612 September 9, 1994
Ricin (blocked) conjugated murine monoclonal antibody (CD6) Cutaneous T-cell lymphomas, acute T-cell leukemia-lymphoma, and related mature T-cell malignancies ImmunoGen, Inc.;830 Winter Street;Waltham, Massachusetts, 02451 September 6, 1994
Somatropin Adults with growth hormone deficiency Pharmacia & Upjohn;7000 Portage Road;Kalamazoo, Michigan, 49001 September 6, 1994
Recombinant vaccinia (human papillomavirus) Cervical cancer Xenova Research Limited;310 Cambridge Science Park, Cambridge CB4 OWG; August 24, 1994
Buffered intrathecal electrolyte/dextrose injection For use as a diluent in the intrathecal administration of methotrexate and cytarabine for the prevention or treatment meningeal leukemia and lymphocytic lymphoma Lukare Medical, LLC;4 Julia Court, P. O. Box 782;Scotch Plains, New Jersey, 07076 August 24, 1994