Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

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Country Product Indication Sponsor Date
Liposomal nystatin Invasive fungal infections The University of Texas;M.D. Anderson Cancer Center, Unit 038;Houston, Texas, 77030 June 13, 2000
Centruroides immune F(ab)2 Scorpion envenomations requiring medical attention Rare Disease Therapeutics, Inc.;12975 Brookprinter Drive, Suite 170;Poway, California, 92064 June 12, 2000
Omega-3 (n-3) polyunsaturated fatty acids IgA nephropathy Pronova Biocare, AS;PO Box 420, 1327 Lysaker; May 4, 2000
Tetraiodothyroacetic acid Suppression of thyroid stimulating hormone in patients with well-differentiated cancer of the thyroid gland Danforth, Jr., MD, Elliot;University of Vermont, 84 Beartown Rd.;Underhill, Vermont, 05489 May 1, 2000
Arsenic trioxide Multiple myeloma TEVA Branded Pharmaceutical Products R & D, Inc.;41 Moores Road;Frazer, Pennsylvania, 19355 April 28, 2000
DNA-lipid complex (DMRIE/DOPE)/plasmid vector (VCL-1102, Vical) expressing human interleukin-2 Renal cancer Vical Incorporated;9373 Towne Center Dr., Suite 100;San Diego, California, 92121 April 28, 2000
Meropenem Cystic fibrosis AstraZeneca Pharmaceuticals;1800 Concord Pike, PO Box 15437;Wilmington, Delaware, 19850 April 27, 2000
Recombinant human antithrombin III Antithrombin III dependent heparin resistance requiring anticoagulation AT III LLC;c/o Genzyme Corporation, 15 Pleasant St. Connector, P.O. Box 9322;Framingham, Massachusetts, 01701 April 6, 2000
Ethyl eicosapentaenoate Huntington disease Laxdale Ltd.;Kings Park House, Laurelhill Business Park, Polmaise Road, Stirling FK7 9JQ; April 6, 2000
IL-4 Pseudomonas Toxin Fusion Protein (IL-4(38-37)-PE38KDEL) Astrocytic glioma Medicenna Therapeutics, Inc.;220-1075 West George Street, Vancouver, British Columbia; April 6, 2000
Cisplatin/epinephrine Squamous cell carcinoma of the head and neck Matrix Pharmaceutical, Inc.;34700 Campus Drive;Fremont, California, 94555 April 3, 2000
3-(3,5-Dimethyl-1H-2ylmethylene)-1,3-dihydro-indol-2-one Von Hippel-Lindau syndrome Sugen, Inc.;230 East Grand Ave.;South San Francisco, California, 94080 March 23, 2000
Synthetic porcine secretin For use in conjunction with diagnostic, therapeutic, or combined diagnostic/therapeutic procedures for pancreatic disorders to increase pancreatic fluid secretion ChiRhoClin, Inc.;15500 Gallaudet Ave.;Silver Spring, Maryland, 20905 March 7, 2000
Synthetic human secretin For use in conjunction with diagnostic, therapeutic, or combined diagnostic/therapeutic procedures for pancreatic disorders to increase pancreatic fluid secretion ChiRhoClin, Inc.;15500 Gallaudet Ave.;Silver Spring, Maryland, 20905 March 7, 2000
Thymalfasin Hepatocellular Carcinoma SciClone Pharmaceuticals, Inc.;950 Tower Lane, Suite 900;Foster city, California, 94404 March 6, 2000
Soluble complement receptor type 1 Prevention of post-cardiopulmonary bypass syndrome in children undergoing cardiopulmonary bypass Avant Immunotherapeutics, Inc.;119 Fourth Ave.;Needham, Massachusetts, 02494 March 6, 2000
Remacemide Huntington disease AstraZeneca LP;725 Chesterbrook Blvd.;Wayne, Pennsylvania, 19087 March 6, 2000
Bis(4-fluorophenyl)phenylacetamide Sickle cell anemia ICAgen Inc.;Ion Channel Advances, PO Box 14487;Durham, North Carolina, 27709 March 2, 2000
Iodine I 131 bis(indium-diethylenetriaminepentaacetic acid)tyrosyllysine/hMN-14 x m734 F(ab’)2 bispecific monoclonal antibody Small-cell lung cancer IBC Pharmaceuticals, L.L.C.;300 American Rd.;Morris Plains, New Jersey, 07950 February 22, 2000
Etarfolatide For the identification of ovarian carcinomas Endocyte, Inc.;3000 Kent Ave., Suite A1-100;West Lafayette, Indiana, 47906 February 16, 2000
Recombinant human insulin-like growth factor-I Short-bowel syndrome as a result of resection of the small bowel or as a result of congenital dysfunction of the intestines GroPep Pty Ltd.;Gate 11, Victoria Dr., Adelaide SA 5000; February 16, 2000
Angiotensin 1-7 Neutropenia associated with autologous bone marrow transplantation Tarix Pharmaceuticals Ltd;12 Bow Street;Cambridge, Massachusetts, 02138 February 16, 2000
Halofuginone Systemic scleroderma Collgard Biopharmaceuticals Ltd.;Textile House, 2 Koifman St., Tel-Aviv 68012; February 7, 2000
Brimonidine Anterior ischemic optic neuropathy Allergan, Inc.;2525 Dupont Dr.;Irvine, California, 92612 February 7, 2000
Hypericin Cutaneous T-cell lymphoma Soligenix, Inc.;29 Emmons Drive, Suite C-10;Princeton, New Jersey, 08540 February 7, 2000