Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Country Product Indication Sponsor Date
Histamine For use as an adjunct to cytokine therapy in the treatment of malignant melanoma EpiCept Corporation;777 Old Saw Mill River Road;Tarrytown, New York, 10591 February 1, 2000
Phenylbutyrate Acute promyelocytic leukemia Elan Drug Delivery, Inc.;1300 Gould Dr.;Gainesville, Georgia, 30504 January 19, 2000
Natural human lymphoblastoid interferon-alpha Behçet’s Disease Amarillo Biosciences, Inc.;4134 Business Park Drive;Amarillo, Texas, 79110 January 18, 2000
1-(11-dodecylamino-10-hydroxyundecyl)-3,7-dimethylxanthine hydrogen methanesulfonate Hormone refractory prostate carcinoma Cell Therapeutics, Inc.;201 Elliott Avenue West, Suite 400;Seattle, Washington, 98119 January 18, 2000
Levodopa and carbidopa Late stage Parkinson's disease AbbVie, Inc.;1 N. Waukegan Road, Building AP30-1;North Chicago, Illinois, 60064 January 18, 2000
Recombinant human keratinocyte growth factor Reducing the incidence and severity of radiation-induced xerostomia Swedish Orphan Biovitrum AB (publ) (SOBI);SE-112 76;Stockholm December 20, 1999
Adenovirus-based vector Factor VIII complementary DNA to somatic cells Hemophilia A GenStar Therapeutics Corporation;10835 Altman Row, Suite 150;San Diego, California, 92121 December 15, 1999
Histamine Adjunct to cytokine therapy in the treatment of acute myeloid leukemia EpiCept Corporation;777 Old Saw Mill River Road;Tarrytown, New York, 10591 December 15, 1999
Ubiquinone Mitochondrial cytopathies Gel-Tec, Division of Tishcon Corp.;30 New York Avenue, P. O. Box 331;Westbury, New York, 11590 December 14, 1999
Pentostatin Peripheral T-cell lymphomas SuperGen, Inc.;4140 Dublin Blvd., Suite 200;Dublin, California, 94568 November 24, 1999
Gemtuzumab ozogamicin Acute myeloid leukemia Wyeth Pharmaceuticals, Inc., a Pfizer Company;10646 Science Center Drive;San Diego, California, 92121 November 24, 1999
Alpha1-proteinase inhibitor (human) For slowing the progression of emphysema in alpha1-antitrypsin deficient patients CSL Behring L.L.C.;1020 First Ave., PO Box 61501;King of Prussia, Pennsylvania, 19406 November 24, 1999
Dimerizing drug that binds to mutated Fas protein/drug-binding domain fusion protein (FKBP) Graft Versus Host Disease Bellicum Pharmaceuticals, Inc.;6400 Fannin Street, Suite 2300;Houston, Texas, 77030 November 24, 1999
Gemtuzumab zogamicin CD33-positive acute myeloid leukemia Wyeth-Ayerst Laboratories;PO Box 8299;Philadelphia, PA, 19101-8299 November 24, 1999
Silver sulfadiazine and cerium nitrate Patients with severe dermal burns Alliance Pharmaceuticals Ltd;Avonbridge House, Bath Road, Chippenham;Wiltshire, SN15 2BB November 17, 1999
Somatropin (rDNA origin) Long-term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion Genentech, Inc.;1 DNA Way;South San Francisco, California, 94080 October 28, 1999
Temoporfin Palliative treatment of recurrent, refractory or second primary squamous cell carcinomas of the head and neck in patients considered to be incurable with surgery or radiotherapy Biolitec Pharma Ireland Ltd.;United Drug House, Dublin; October 28, 1999
Teriparatide Idiopathic osteoporosis Biomeasure, Inc.;27 Maple St.;Milford, Massachusetts, 01757 October 28, 1999
Botulinum toxin type A Dynamic muscle contractures in pediatric cerebral palsy patients Ipsen Limited;1 Bath Rd., Maidenhead;Berkshire SL6 4UH October 20, 1999
L-glutamyl-L-tryptophan AIDS-related Kaposi's sarcoma Implicit Bioscience Pty Ltd;P. O. Box 2072., Toowong Business Center; October 20, 1999
Amifostine Myelodysplastic syndromes Clinigen Group plc;Pitcairn House, Crown Square, DE14 2WW; October 4, 1999
Peginterferon alfa-2a Chronic myeloid leukemia Hoffman-La Roche Inc.;340 Kingsland St.;Nutley, New Jersey, 07110 September 30, 1999
HLA-B7/Beta2M DNA Lipid (DMRIE/DOPE) Complex Metastatic Melanoma Vical Incorporated;9373 Towne Centre Dr., Suite 100;San Diego, California, 92121 September 30, 1999
Azathioprine Oral manifestations of graft-versus-host disease Oral Solutions, Inc.;787 Seventh Ave., 48th Floor;New York, New York, 10019 September 14, 1999
Epirubicin Breast cancer Pharmacia & Upjohn Company;0634-298-113, 7000 Portage Rd.;Kalamazoo, Michigan, 49001 September 14, 1999