Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

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Country Product Indication Sponsor Date
Chimeric monoclonal antibody to CD30 (anti-CD30 antibody) CD30 positive T-cell lymphomas Seattle Genetics, Inc.;21823 30th Drive Southeast;Bothell, Washington, 98021 February 18, 2004
Antivenin crotaline (pit-viper) equine immune F(ab)2) Envenomation by Crotaline snakes Rare Disease Therapeutics, Inc.;12975 Brookprinter Place, Suite 170;Poway, California, 92064 January 29, 2004
90Y-hPAMA4 Pancreatic Cancer Immunomedics, Inc.;300 American Road;Morris Plains, New Jersey, 07950 January 29, 2004
(1S)-1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol-hydrochloride T-cell lymphoma Mundipharma Research Limited;Cambridge Science Park, Cambridge CB4 0GW;England January 29, 2004
Chenodeoxycholic acid Cerebrotendinous xanthomatosis Dr. Falk Pharma GmbH;Leinenweberstrasse 5, 9041 Freiburg, GERMANY; January 29, 2004
Staphylococcus aureus Immune Globulin (Human) Prophylaxis against Staphylococcus aureus infections in low birth weight neonates Biotest Pharmaceuticals Corporation;5800 Park of Commerce Blvd, NW;Boca Raton, Florida, 33487 January 29, 2004
3-(4’aminoisoindoline-1′-one)-1-piperidine-2,6-dione Incontinentia pigmenti Celgene Europe Limited December 12, 2003
N-acetyl-sarcosyl-glycyl-L-valyl-D-alloisoleucyl-L-threonyl-L-norvalyl-L-isoleucyl-L-arginyl_L-prolylethylaminde acetate Soft tissue sarcoma AbbVie, Inc.;1 N. Waukegan Road;North Chicago, Illinois, 60064 December 9, 2003
Baclofen Dystonia Medtronic Neurological;710 Medtronic Parkway NE;Minneapolis, Minnesota, 55432 December 2, 2003
2-(3-diethylaminopropyl)-8,8-dipropyl-2-azaspiro [4,5] decan dimaleate Mulitple myeloma and associated bone resorption Callisto Pharmaceuticals, Inc.;2 Executive Drive, Suite 450;Somerset, New Jersey, 08873 December 2, 2003
Tranilast Glioma Angiogen Pharmaceuticals, Pty. Ltd.;Level 31, ABN AMRO Tower, 88 Phillip Street Sydney, N.S.W. 2000; December 2, 2003
Cyclosporine Acute rejection in patients requiring allogenic lung transplants APT Pharmaceuticals, Inc.;700 Airport Blvd., Suite 350;Burlingame, California, 94010 November 25, 2003
Cyclosporine Prophylaxis of organ rejection in patients receiving allogeneic lung transplant APT Pharmaceuticals, Inc.;700 Airport Blvd., Suite 350;Burlingame, California, 94010 November 25, 2003
Hydroxocobalamin Acute cyanide poisoning SERB, S.A.;480 Avenue Louise;Brussels November 25, 2003
Abagovomab Ovarian epithelial cancer Menarini Ricerche S.p.A.;Via Tito Speri 10, Pomezia Roma; November 25, 2003
Anti-interferon-gamma Fab from goats For the treatment of immunologic corneal allograft rejection Advanced Biotherapy, Inc.;6355 Topanga Canyon Blvd., Suite 510;Woodland Hills, California, 91367 November 18, 2003
Infliximab pediatric Crohn’s disease Centocor, Inc.;200 Great Valley Parkway;Malvern, Pennsylvania, 19355 November 12, 2003
SC-1 monoclonal antibody Patients with CD55 (sc-1) positive gastric tumors Patrys Limited;Suite 614, Level 6, Equitable House, Melbourne, Victoria 3000; November 12, 2003
Coagulation factor XIII A-subunit (recombinant) Factor XIII Deficiency Novo Nordisk, Inc.;800 Scudders Mill Rd.;Plainsboro, New Jersey, 08536 November 6, 2003
Bevacizumab Renal cancer Genentech, Inc.;1 DNA Way;South San Francisco, California, 94080 November 6, 2003
[5,10,15,20-tetrakis(1,3-diethylimidazolium-2-yl)porphyrinato] manganese(III)pentachloride Amyotrophic lateral sclerosis Aeolus Pharmaceuticals, Inc.;PO Box 14287; 79 T.W. Alexander Dr., Suite 200;Research Triangle Park, North Carolina, 27709 November 4, 2003
Imexon Pancreatic adenocarcinoma AmpliMed Corporation;4380 North Campbell Avenue, Suite 205;Tucson, Arizona, 85718 November 1, 2003
Herpes simplex 1 virus-thymidine kinase and truncated low affinity nerve growth factor receptor transfected donor lymphocytes Adjunctive treatment in hematopoietic cell transplantation MolMed S.p.A. October 20, 2003
Atomoxetine hydrochloride Tourette syndrome Eli Lilly & Company;Lilly Corporate Center;Indianapolis, Indiana, 46285 August 26, 2003
5,5′,5″-[Phosphinothioylidyne-tris(imino-2,1-ethanediyl)]tris[5-methylchelidoninium]trihydroide hexahydrochloride Pancreatic Cancer Now Pharm AG;241, route d'Arlon, L-1150; August 20, 2003