BOSTON, Mass. — Brain disorders like Parkinson’s (PD) or Alzheimer’s Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at...
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Chicago, Illinois – Immunotherapy before surgery for patients with metastatic melanoma appears to be especially successful. Fifty-nine percent of patients responds so well to this therapy that adjuvant treatment is no longer needed, according to the results of the NADINA study that were published today. The NADINA study, led by...
San Francisco, Calif. – Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed. But now, UC San Francisco researchers have found a way to identify the condition while patients are still alive. A study appearing in Neurology on...
MINNEAPOLIS/ST. PAUL, Minn. — For the first time, researchers at the University of Minnesota Twin Cities showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior. This is a major step forward for discovering new therapies to treat brain disorders such as...
BEER-SHEVA and TEL AVIV, Israel – Ben-Gurion University (BGU) of the Negev’s Prof. Gad Vatine and Tel Aviv University’s Dr. Avraham Ashkenazi are up and coming young principal investigators. Vatine is an expert in studying rare disorders using patient-specific stem cells, and Ashkenazi is an expert in tri-nucleotide repeat expansion...
London, UK – The phase 3 clinical trial, led by Professor Peter Szlosarek at Queen Mary and sponsored by Polaris Pharmaceuticals, has unveiled a breakthrough in the treatment of malignant pleural mesothelioma (MPM), a rare and often rapidly fatal form of cancer with limited therapeutic options. The ATOMIC-meso trial, a...
Oxford, UK – Researchers from the University of Oxford have identified a key biochemical mechanism relevant to the development of Huntington’s Disease. This discovery opens up the possibility of studying the disease before its clinical onset and eventually stopping its progression. The study, published in Nature Metabolism, has shown for...
Rio de Janeiro, Brazil – Research from the Federal University of Rio de Janeiro (UFRJ) and the National Institute of Science and Technology for Structural Biology and Bioimaging (INBEB) in Brazil has uncovered a critical mechanism by which mutations in the p53 protein—a key tumor suppressor known as the “guardian...
Darlinghurst, Australia – A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint inhibitors experience increased susceptibility to common infections. The findings, published in the journal Immunity, provide new insights into immune...
Nottingham, England – Experts have used a cutting-edge computational approach to discover the genetic factors that make the bacteria behind cholera so dangerous – which could be key to preventing this deadly disease. The breakthrough study, published in Nature Communications, is led by Professor Tania Dottorini from the University of...