PHILADELPHIA, Pa. — Only a very small percentage of neurons show changes after an epileptic seizure in mice, but these alterations can be permanent and trigger future seizures that can affect the whole brain and lead to impaired cognition, like memory and learning, according to new research from the Perelman...
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Washington, D.C – High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD), according to a study conducted in mice. The study was published in mSystems, a journal of the American...
People with severe pulmonary arterial hypertension (PAH) who respond strongly to early treatment with prostacyclin infusions may eventually be able to reduce or discontinue the therapy while maintaining long-term improvements, according to a study. In a long-term analysis of 101 patients with severe PAH, about one in five improved enough...
Phase 1 trial demonstrates encouraging clinical activity of investigational immunotherapy for relapsed or refractory multiple myeloma Novel investigational dual-antigen-targeting immunotherapy binds to B-cell maturation antigen (BCMA) and GPRC5D on myeloma cells, as well as CD3 on T-cells CHICAGO, Ill. — Johnson & Johnson announced initial Phase 1 results of JNJ-79635322 (JNJ-5322), a novel...
Motor and memory training early in life postpones the onset of difficulties in those areas in a mouse model of Rett syndrome, according to a study published today in Nature. Stimulating neurons involved in those skills appears to mimic the effects of training. Mutations in the gene MECP2 cause Rett syndrome, which often overlaps with...
Cambridge, England – An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage. The study, led by...
HOUSTON, TX ― Incorporating navy beans into the diet of colorectal cancer (CRC) survivors has the potential to positively impact both gut and host health by modulating markers linked to obesity and disease, according to new research from The University of Texas MD Anderson Cancer Center. The findings published today in...
Sugar Land, TX – Obesity is a chronic metabolic disease associated with the development of several other metabolic disease, including cancer. The present study aims to evaluate the eating habits, physical activity, and clinical profiles of colorectal cancer (CRC) patients with overweight/obesity. Methods A cross-sectional study was conducted with data...
Philadelphia – Thanksgiving is often a time for thinking about your belly. For those with an inflammatory bowel diseases like ulcerative colitis, feasting can be associated with stress, even when food isn’t a trigger for the painful symptoms. New research in mice suggests that certain foods – especially those high...
BEERSE, Belgium – Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved an indication extension of DARZALEX® (daratumumab) subcutaneous (SC) formulation in the frontline setting. The approval is for daratumumab SC in combination with bortezomib, lenalidomide, and dexamethasone (daratumumab-VRd) for the treatment...