Diseases

Transposition of great arteries

Transposition of the great arteries is a congenital (present at birth) heart defect. Due to abnormal development of the fetal heart during the first 8 weeks of pregnancy, the large vessels that take blood away from the heart to the lungs, or to the body, are improperly connected. Normally, oxygen-poor (blue) blood returns to the right atrium from the body, travels to the right ventricle, then is pumped through the pulmonary artery into the lungs where it receives oxygen. Oxygen-rich (red) blood returns to the left atrium from the lungs, passes into the left ventricle, and then is pumped through the aorta out to the body.

Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Transthyretin amyloid cardiomyopathy is a rare but severe cause of restrictive cardiomyopathy, caused by the accumulation of transthyretin fibrils in the myocardium. It can present with new or worsening heart failure or new conduction system disease. Due to the lack of knowledge and efficient diagnostic modalities, this disease was often missed in clinical settings. However, with the advent of contemporary cardiac imaging techniques and effective therapeutic options, early diagnosis and treatment are possible. This activity reviews the pathophysiology, diagnosis, and treatment of Transthyretin amyloid cardiomyopathy and highlights the role of the interprofessional team in evaluating and treating patients with this condition.

Transverse limb deficiency hemangioma

Transverse limb deficiency hemangioma (medical condition): See Transverse limb deficiency - hemangioma (disease information). Transverse limb deficiency - hemangioma: A rare disorder characterized by missing or short bones in a limb as well as a hemangioma

Transverse myelitis

Transverse myelitis is a neurological condition in which the spinal cord is inflamed. The inflammation damages nerve fibers, and causes them to lose their myelin coating leading to decreased electrical conductivity in the central nervous system. Transverse implies that the inflammation extends across the entire width of the spinal cord. Partial transverse myelitis and partial myelitis are terms used to define inflammation of the spinal cord that affects part of the width of the spinal cord.

Treacher Collins syndrome

Treacher Collins syndrome (TCS) is a rare autosomal dominant congenital disorder characterized by craniofacial deformities, such as absent cheekbones. Treacher Collins syndrome is found in about one in 50,000 births. The typical physical features include downward-slanting eyes, micrognathia (a small lower jaw), conductive hearing loss, underdeveloped zygoma, drooping part of the lateral lower eyelids, and malformed or absent ears.

Tremor hereditary essential- 1

Tremor hereditary essential, 1: An inherited movement disorder involving tremors which occurs mainly in the arms but other parts of the body are often involved. Any kind of stress on the body such as hunger and tiredness can aggravate the condition.

Tremor hereditary essential- 2

Tremor hereditary essential, 2: An inherited movement disorder involving tremors. Any kind of stress on the body such as hunger and tiredness can aggravate the condition.

Treponema infection

Treponema infection: A rare infectious diseases which is transmitted through sexual contact and caused by Treponema pallidum (a spirochete bacterium). Untreated cases can result in severe complications and even death.

Trichinellosis

Trichinosis, also called trichinellosis, or trichiniasis, is a parasitic disease caused by eating raw or undercooked pork and wild game infected with the larvae of a species of roundworm Trichinella spiralis, commonly called the trichina worm. The few cases in the United States are mostly the result of eating undercooked game, bear meat, or home reared pigs. It is most common in the developing world and where pigs are commonly fed raw garbage

Tricho onychic dysplasia

Tricho-onychic dysplasia: A rare genetic syndrome characterized by hair and nail abnormalities.

Tricho-dento-osseous syndrome

A rare genetic disorder characterized by kinky hair, tooth enamel and bone abnormalities. There are two different subtypes with type I being distinguished from type II by the presence of a small head and increased density in the long bones

Tricho-hepato-enteric syndrome

Tricho-hepato-enteric syndrome (THE), also known as syndromic or phenotypic diarrhea, is an extremely rare congenital bowel disorder which manifests itself as intractable diarrhea in infants with intrauterine growth retardation, hair and facial abnormalities

Trichoepithelioma multiple familial

An inherited skin disorder characterized by a number of small tumors that occur on the face. The number of tumors is variable with most of the face being covered in some cases.

Trichofolliculoma

A benign hair tumor which looks like a small lump with a tuft of hair growing out of it. The hair is often white and short. They often occur around the nose area.

Trichomalacia

A rare genetic condition resulting in patchy hair loss in children. It is an abnormality of the hair shaft and can be due to a compulsive habit of pulling hair on the head or even eyelashes and eyebrows

Trichomegaly cataract hereditary spherocytosis

A rare syndrome characterized mainly by cataracts, excessive eyelash growth and and a blood abnormality (the red blood cells are spherical instead of doughnut shaped which makes them fragile).