Diseases

Trichostasis spinulosa

Trichostasis spinulosa is also called “bundle bush hair”. Instead of one hair protruding from a hair follicle, bundle or bush of hair come out of a single follicle. It has no pathological significance.

Trichothiodystrophy

A rare inherited skin disorder characterized by red, dry, scaly skin (I - ichthyosis), brittle hair (B), impaired physical and mental development (I), decreased fertility (D) and short stature (S). It is the same as PIBIDS syndrome but doesn't involve photosensitivity.

Trichotillomania

Trichotillomania is hair loss caused by compulsive pulling or twisting of the hair until it breaks off.

Tricuspid atresia

Tricuspid atresia is a type of congenital heart disease in which the tricuspid heart valve is missing or abnormally developed. The defect blocks blood flow from the right atrium to the right ventricle.

Triopia

Triopia: An extremely rare malformation characterized by the presence of an extra eye.

Triphalangeal thumb non opposable

Triphalangeal thumb, non opposable: A thumb deformity where the thumb looks like a finger - it has three bones instead of the normal two. The hand appears to have five fingers instead of 4 fingers and a thumb.

Triphalangeal thumbs brachyectrodactyly

Triphalangeal thumbs brachyectrodactyly: Another name for Carnevale-Hernandez-Castillo syndrome (or close medical condition association). Carnevale-Hernandez-Castillo syndrome: An extremely rare disorder characterized by missing digits or parts of digits and a thumb that has three bones like a finger instead of the normal two.

triple-negative breast cancer

Triple-negative breast cancer (TNBC) accounts for about 10-15% of all breast cancers. The term triple-negative breast cancer refers to the fact that the cancer cells don’t have estrogen or progesterone receptors (ER or PR) and also don’t make any or too much of the protein called HER2. (The cells test “negative” on all 3 tests.) These cancers tend to be more common in women younger than age 40, who are Black, or who have a BRCA1 mutation. TNBC differs from other types of invasive breast cancer in that it tends to grow and spread faster, has fewer treatment options, and tends to have a worse prognosis (outlook).

Trisomy 1 mosaicism

Trisomy 1 mosaicism: A very rare chromosomal disorder where there is an extra copy of chromosome 1 in some of the body's cells. This chromosomal abnormality is believed to result in death of the fertilized cells even before implantation in the uterus and hence no fetus ever develops with this disorder.

Trisomy 11 mosaicism

Trisomy 11 mosaicism: A very rare chromosomal disorder where there is an extra copy of chromosome 11 in some of the body's cells. Generally this chromosomal abnormality has not presented with any clinical symptoms that have been reported.

Trisomy 12 mosaicism

Trisomy 12 mosaicism: A very rare chromosomal disorder where there is an extra copy of chromosome 12 in some of the body's cells. Some cases with this chromosomal abnormality have no clinical symptoms. The presence of abnormalities in some cases is dependent on which body cells contain the chromosomal defect.

Trisomy 2 mosaicism

Trisomy 2 mosaicism: A rare chromosomal disorder where there is an extra copy of chromosome 2 in some of the body's cells. Most cases with this chromosomal abnormality have no clinical symptoms. The presence of abnormalities in some cases is dependent on which body cells contain the chromosomal defect.

Trisomy 3 mosaicism

Trisomy 3 mosaicism: A very rare chromosomal disorder where there is an extra copy of chromosome 3 in some of the body's cells. Some cases with this chromosomal abnormality have no clinical symptoms. The presence of abnormalities in some cases is dependent on which body cells contain the chromosomal defect.

Trisomy 6

Trisomy 6 mosaicism: A very rare chromosomal disorder where there is an extra copy of chromosome 6 in some of the body's cells. Some cases with this chromosomal abnormality have no clinical symptoms. The presence of abnormalities in some cases is dependent on which body cells contain the chromosomal defect.

Trochlear dysplasia

Trochlear dysplasia: An unstable kneecap due to abnormal development of the kneecap.

Tropical Spastic Paraparesis

Main name of condition: Tropical Spastic Paraparesis.

Other names or spellings for Tropical Spastic Paraparesis: Tropical spastic paraplegia, Retrovirus-Associated Myelopathy, HTLV-1 Associated Myelopathy, TSP, Cassava syndrome, ataxic neuropathy of Nigeria

Tropical Spastic Paraparesis: A form of spastic partial paralysis of the lower limbs which occurs in the tropics. Tropical Spastic Paraparesis: A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by human T-cell leukemia virus type I (HUMAN T-LYMPHOTROPIC VIRUS 1). Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord .

Tropical sprue

Tropical sprue is a condition affecting the absorption of nutrients (malabsorption) that is common in the tropics and subtropics.

Trueb Burg Bottani syndrome

Trueb-Burg-Bottani syndrome: A very rare genetic syndrome characterized by hair, teeth and nail abnormalities as well as webbed fingers.

Trypanosomiasis- east-African

African trypanosomiasis [tri-PAN-o-SO-my a-sis], also called sleeping sickness, is a serious parasitic disease that is always fatal without treatment. The disease is spread by the bite of tsetse flies, found only in Africa. It occurs in two forms: East African trypanosomiasis and West African trypanosomiasis. There is no vaccine or drug to prevent African trypanosomiasis. Travelers to areas where the disease occurs should take precautions to avoid tsetse fly bites. African trypanosomiasis, also called sleeping sickness, is a serious tropical disease that is always fatal without treatment. There are two types of African trypanosomiasis, named for the regions in Africa in which they are found: East African trypanosomiasis and West African trypanosomiasis.

Trypanosomiasis- west African

A hemoflagellate subspecies of parasitic protozoa that causes Gambian or West African sleeping sickness in humans. The vector host is usually the tsetse fly (Glossina).

Tsao Ellingson syndrome

Tsao-Ellingson syndrome: A very rare syndrome characterized mainly by spasms during infancy and broad thumbs.

Tsukahara Azuno Kajii syndrome

Tsukahara azuno kajii syndrome: Another name for Brachydactyly - dwarfism - mental retardation (or close medical condition association). Brachydactyly - dwarfism - mental retardation: A very rare syndrome characterized by short fingers, very short stature and mental retardation.

Tsukahara Kajii syndrome

Tsukahara kajii syndrome: Another name for Hypertrichosis, anterior cervical (or close medical condition association). Hypertrichosis, anterior cervical: A very rare syndrome characterized by abnormal and excessive hair growth at the front of the neck. The hair abnormality usually becomes apparent around the age of 3. Usually no other abnormalities are present.

Tsukuhara syndrome

Tsukuhara syndrome: A very rare syndrome characterized mainly by a curved spine, premature fusion of skull bones and a small head.