A hip joint disorder where bone growth abnormalities caused by an interrupted blood supply to the head of the femoral bone results in it's degeneration and deformity. When the body creates a new blood supply, new healthy bone can be formed.
Osteochondritis dissecans is a joint condition in which bone underneath the cartilage of a joint dies due to lack of blood flow. This bone and cartilage can then break loose, causing pain and possibly hinder joint motion.
Osteochondritis dissecans occurs most often in children and adolescents. It can cause symptoms either after an injury to a joint or after several months of activity, especially high-impact activity such as jumping and running, that affects the joint. The condition occurs most commonly in the knee, but also occurs in elbows, ankles and other joints.
Doctors stage osteochondritis dissecans according to the size of the injury, whether the fragment is partially or completely detached, and whether the fragment stays in place. If the loosened piece of cartilage and bone stays in place, you may have few or no symptoms. For young children whose bones are still developing, the injury might heal by itself.
Surgery might be necessary if the fragment comes loose and gets caught between the moving parts of your joint or if you have persistent pain.
However, affected people may experience pain, weakness and/or decreased range of motion in the affected joint if the cartilage and bone travel into the joint space. Although osteochondritis dissecans can affect people of all ages, it is most commonly diagnosed in people between the ages of 10 and 20 years.
Risk factors:
Osteochondritis dissecans occurs most commonly in children and adolescents between the ages of 10 and 20 who are highly active in sports.
Complications:
Osteochondritis dissecans can increase your risk of eventually developing osteoarthritis in that joint.
A very rare syndrome characterized by excess fluid in the skull, a blood disorder and bone and bone abnormalities.
Also called osteocartilaginous exostoses, osteochondroma is an overgrowth of cartilage and bone near the end of the bone near the growth plate. This type of overgrowth can occur in any bone where cartilage eventually forms bone. Most commonly, it affects the long bones in the leg, the pelvis, or scapula (shoulder blade). Osteochondroma is the most common benign (non-cancerous) bone growth. The lesion usually occurs during skeletal growth - between the ages of 10 and 30 years. It affects males and females equally.
A rare joint disorder where some of the tissue that lines the joint is replaced by bone-like tissue or cartilage. Usually only one joint is affected and it tends to be the knee, elbow or hip.
A very rare syndrome
A rare form of recessively inherited severe dwarfism.
A very rare fatal disorder characterized by abnormal bone development and growth failure. Death occurs within the first year of life.
Familial osteoectasia (juvenile Paget disease, hyperostosis corticalis deformans juvenilis, chronic congenital idiopathic hyperphosphatasemia) is a familial disorder that manifests early in life with a large head due to a extremely thick calvaria with islands of increased none density.
Osteogenesis imperfecta (OI, also known as brittle bone disease or Lobstein syndrome),is a congenital bone disorder characterized by brittle bones that are prone to fracture. OI may also present with shorter height, neurological features including communicating hydrocephalus, basilar invagination, and seizures, blue sclerae, hearing loss, or other complications. The fractures themselves can cause acute or chronic pain, reduced quality of life, and depression.
People with OI are born with defective connective tissue, or without the ability to make it, usually because of a deficiency of type I collagen. Eight types of OI can be distinguished. Most cases are caused by mutations in the COL1A1 and COL1A2 genes, both of which code for type I collagen. Diagnosis of OI is based on the clinical features and may be confirmed by collagen or DNA testing.
There is no cure for OI. Treatment is aimed at increasing overall bone strength to prevent fracture and maintain mobility. Treatment includes bisphosphonates, surgery, physical therapy, and physical aids.
OI occurs in about one per 20,000 live births. The frequency of OI doesn't change across groups, but certain types are more common in certain groups.
A rare genetic connective tissue disorder charactedrized by blue sclerae, cataracts and microcephaly - a lethal form of osteogenesis imperfecta.
A genetic bone disorder which causes fragile bones.
An inherited connective tissue disorder featuring bone fragility and blue sclerae (blue whites of the eyes). This is the classic form of "brittle bone disease." Osteogenesis imperfecta type 1 is an autosomal dominant trait. (One copy of the mutant gene is enough to cause the disease in males and females in successive generations.)
A rare genetic connective tissue disorder characterized by fragile bones and hyperextensible joints - a type of osteogenesis imperfecta I where the teeth are opalescent and blue sclerae may be absent.
rare lethal form of a genetic connective tissue disorder characterized by fragile bones, blue sclerae and facial and tooth abnormalities. Type IIA has a different origin of the genetic mutation but the clinical features are similar. Type IIA involves a defect on the COL1A2 gene. The main difference is that type IIA tends to involve a large head and dark blue eyes.
An inherited connective tissue disorder with extremely severe bone fragility. This is the lethal form of "brittle bone disease." Osteogenesis imperfecta type 2 is a recessive trait with males and females affected. Two copies of the mutant gene are needed to cause the disease.
Osteogenesis imperfecta is a group of inherited disorders that mainly affect the bones, causing them to be fragile and easily broken. Type III is a severe form of the disorder; its signs and symptoms fall between the very severe osteogenesis imperfecta type II and the milder osteogenesis imperfecta type I. Osteogenesis imperfecta, type III is a subtype of osteogenesis imperfecta
rare genetic connective tissue disorder characterized by fragile bones and blue sclerae - a form of OI involving moderate osteoporosis and no joint hyperextensibility.
A rare genetic connective disuse disorder characterized by fragile bones, calcification of membranes between bones and hypertrophic calluses.
A rare form of the genetic connective tissue disorder characterized by fragile bones and light-colored eyes. There are a number of types of osteogenesis imperfecta and type 6 is considered a moderate to severe form.
A rare connective tissue disorder characterized by fragile bones. Type VII is a severe form of the condition which is recessively inherited.
A form of connective tissue disorder involving fragile bones. Type VIII is distinguished from the other types of osteogenesis imperfecta by white sclerae, severely reduced bone mineralization and abnormal metaphyses.
A form of dwarfism characterized by premature fusion of skull bones, short limbs and digits, facial abnormalities and bone development anomalies.
A very rare skeletal disorder characterized by bone loss in the hand and foot bones (carpals and tarsals) as well as abnormalities involving the long bones and digits.
Osteomalacia is the general term for the softening of the bones due to defective bone mineralization. Osteomalacia in children is known as rickets, and because of this, osteomalacia is often restricted to the milder, adult form of the disease. It may show signs as diffuse body pains, muscle weakness, and fragility of the bones. A common cause of the disease is a deficiency in Vitamin D, which is normally obtained from the diet and/or sunlight exposure.
Osteomyelitis is an infection in a bone. Infections can reach a bone by traveling through the bloodstream or spreading from nearby tissue. Osteomyelitis can also begin in the bone itself if an injury exposes the bone to germs.
In children, osteomyelitis most commonly affects the long bones of the legs and upper arm, while adults are more likely to develop osteomyelitis in the bones that make up the spine (vertebrae). People who have diabetes may develop osteomyelitis in their feet if they have foot ulcers.
It is the death of bone tissue due to a lack of blood supply. Also called osteonecrosis, avascular necrosis can lead to tiny breaks in the bone and the bone's eventual collapse.
The blood flow to a section of bone can be interrupted if the bone is fractured or the joint becomes dislocated. Avascular necrosis is also associated with long-term use of high-dose steroid medications and excessive alcohol intake.
Anyone can be affected by avascular necrosis. However, it's most common in people between the ages of 30 and 60. Because of this relatively young age range, avascular necrosis can have significant long-term consequences.
Osteonecrosis can be in one or several bones. It is most common in the upper leg. Other common sites are your upper arm and your knees, shoulders and ankles. The disease can affect men and women of any age, but it is mention above it usually strikes in thirties, forties or fifties.
A rare disorder characterized by striations along most long bones as well as increased bone density in the skull which is associated with various craniofacial defects.
A rare disorder characterized by longitudinal striations on long bones and pigmentation abnormalities affecting the skin and hair.