Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner and QST

Brief Title

Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner and QST

Official Title

Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner

Brief Summary

      Erythromelalgy (EM) is a vascular syndrome very rare affecting the feet. This disease evolve
      by crisis when the feet extremities become red hot and painful. There are several types of EM
      but this study concern the adult primitive form. For a long time, the physiopathology was not
      described but now we know that there is a vascular form, with microcirculatory dysfunction
      and a neurologic form with small fibers neuropathy. The diagnostic of neurologic form is
      based on clinical evaluation (DN4 questionnaire, UENS scale...) and an electromyography.
      Thermotest, a medical device which measure the thermic sensitivity is used to quantify
      neuropathy. More recently Sudoscan, a device measuring cutaneous impedance to chloride ions
      detect small nervous fiber in diabetic patients with good correlation with Thermotest.

      The purpose of this study is to analyze the vascular side and the neurologic side on patients
      consulting for Erythromelalgy.
    



Study Type

Interventional


Primary Outcome

Assessment of Chlorine ion production change


Condition

Erythermalgia

Intervention

impedance measurement and pain evaluation

Study Arms / Comparison Groups

 erythermalgia patient
Description:  patient will be measured chlorine ions impedance with the SUDOSCAN and evaluation on pain du to temperature with the THERMOTEST

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Other

Estimated Enrollment

33

Start Date

January 12, 2017

Completion Date

April 17, 2019

Primary Completion Date

January 18, 2018

Eligibility Criteria

        Inclusion Criteria:

          -  Pain with burn feeling at hands and feet extremities

          -  Crisis activated by the heat

          -  Age > 18 years old

        Exclusion Criteria:

          -  Patients who had burn in extremities
      

Gender

All

Ages

18 Years - N/A

Accepts Healthy Volunteers

No

Contacts

, , 

Location Countries

France

Location Countries

France

Administrative Informations


NCT ID

NCT03044340

Organization ID

ERYTHROMELALGY


Responsible Party

Sponsor

Study Sponsor

Groupe Hospitalier Paris Saint Joseph


Study Sponsor

, , 


Verification Date

April 2019