University of Miami – Anemia

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The purpose of this protocol is to provide treatment with HBOC-201 to patients with
life-threatening anemia for whom blood is not an option. Such patients may also be referred
to in this document as patients who refuse blood transfusion (PWRBT). Other patients who
potentially may require HBOC-201 treatment include those with red blood cell alloantibodies
for whom immunologically compatible red blood cell units cannot be found, although these
patients are less common than PWRBT.

Rare Disease: