Brief Title
Use of Ketamine Prior to Cardiopulmonary Bypass in Children
Official Title
Use of Ketamine Prior to Cardiopulmonary Bypass in Children
Brief Summary
To assess whether the drug ketamine given prior to cardiopulmonary bypass can decrease injury to the cells in the brain.
Study Phase
Phase 2
Study Type
Interventional
Primary Outcome
To compare expression of serum markers of CNS injury
Secondary Outcome
to compare the clinical, radiological and neurodevelopmental outcomes of the cases and controls
Condition
Ventricular Septal Defect
Intervention
saline
Study Arms / Comparison Groups
1
Description:
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Drug
Estimated Enrollment
24
Start Date
July 2004
Completion Date
November 2007
Eligibility Criteria
Inclusion Criteria: - less than one year of age - undergoing cardiac surgery for repair of ventricular septal defect - requiring cardiopulmonary bypass - not requiring retrogrades cerebral perfusion Exclusion Criteria: - Downs Syndrome
Gender
All
Ages
N/A - 1 Year
Accepts Healthy Volunteers
No
Contacts
Adnan T Bhutta, MD, ,
Location Countries
United States
Location Countries
United States
Administrative Informations
NCT ID
NCT00556361
Organization ID
28781 Bhutta
Secondary IDs
CUMG
Study Sponsor
Arkansas Children's Hospital Research Institute
Study Sponsor
Adnan T Bhutta, MD, Principal Investigator, Arkansas Children's Hospital Research Institute
Verification Date
November 2007