Optimal Timing for Repair of Left to Right Shunt Lesions

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Ventricular septal defects
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Brief Title

Optimal Timing for Repair of Left to Right Shunt Lesions

Official Title

Optimal Timing for Repair of Left-to-Right Shunt Lesions

Brief Summary

      The purpose of this study is to determine the optimal timing for repair of left-to-right
      shunt lesions such as ventricular septal defects and atrioventricular canals.

Detailed Description

      In the past, children with left-to-right shunt lesions such as ventricular septal defects and
      atrioventricular canal defects were palliated with a pulmonary artery band. This prevented
      injury to the pulmonary vasculature while the child grew to a size where complete repair
      could be undertaken. With the improvements in surgical technique and critical care, there is
      a push to do a primary complete repair for these defects at younger and younger ages. These
      operations should be delayed as long as possible to allow for growth but not so long that
      there is unnecessary heart failure and medication requirements. The primary aim is to
      determine the optimal timing for repair of left-to-right shunt lesions such as ventricular
      septal defects and atrioventricular canals. The secondary aim is to define the criteria for
      failing medical anti-congestive heart failure therapy. This study will be conducted through a
      retrospective chart review.

Study Type

Observational

Condition

Ventricular Septal Defects

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Estimated Enrollment

200

Start Date

May 2005

Completion Date

August 2007

Eligibility Criteria

        Inclusion Criteria:

          -  Patients in the congenital surgery database

          -  Patients who have undergone repair of ventricular septal defects

          -  Patients who have undergone repair of atrioventricular canal defects

Gender

All

Ages

N/A - N/A

Accepts Healthy Volunteers

No

Contacts

Brian Kogon, MD, ,

Location Countries

United States

Location Countries

United States

Administrative Informations

NCT ID

NCT00229827

Organization ID

05-092

Study Sponsor

Children's Healthcare of Atlanta

Study Sponsor

Brian Kogon, MD, Principal Investigator, Emory University

Verification Date

May 2007