Brief Title
Optimal Timing for Repair of Left to Right Shunt Lesions
Official Title
Optimal Timing for Repair of Left-to-Right Shunt Lesions
Brief Summary
The purpose of this study is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals.
Detailed Description
In the past, children with left-to-right shunt lesions such as ventricular septal defects and atrioventricular canal defects were palliated with a pulmonary artery band. This prevented injury to the pulmonary vasculature while the child grew to a size where complete repair could be undertaken. With the improvements in surgical technique and critical care, there is a push to do a primary complete repair for these defects at younger and younger ages. These operations should be delayed as long as possible to allow for growth but not so long that there is unnecessary heart failure and medication requirements. The primary aim is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals. The secondary aim is to define the criteria for failing medical anti-congestive heart failure therapy. This study will be conducted through a retrospective chart review.
Study Type
Observational
Condition
Ventricular Septal Defects
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
200
Start Date
May 2005
Completion Date
August 2007
Eligibility Criteria
Inclusion Criteria: - Patients in the congenital surgery database - Patients who have undergone repair of ventricular septal defects - Patients who have undergone repair of atrioventricular canal defects
Gender
All
Ages
N/A - N/A
Accepts Healthy Volunteers
No
Contacts
Brian Kogon, MD, ,
Location Countries
United States
Location Countries
United States
Administrative Informations
NCT ID
NCT00229827
Organization ID
05-092
Study Sponsor
Children's Healthcare of Atlanta
Study Sponsor
Brian Kogon, MD, Principal Investigator, Emory University
Verification Date
May 2007