Brief Title
Tracheobronchomalacia: Treatment Outcomes
Official Title
Tracheobronchomalacia: Treatment Outcomes
Brief Summary
The purpose of this study is to evaluate respiratory symptoms and their impact in the quality of life and after treatment of the respiratory condition (tracheobronchomalacia - TBM).
Detailed Description
TBM is an abnormal collapse of the tracheal and bronchial walls. It is characterized by flaccidity of the supporting tracheal and bronchial structures and a significant reduction of airway diameter on expiration seen in the trachea and/or in the mainstem bronchi. Currently there is no available data on the efficacy of central airway stabilization for treating TBM. Our study would provide this important information and would establish the effect of central airway stabilization on symptoms, functional status, quality of life, lung function and exercise capacity in patients with symptomatic and severe TBM.
Study Type
Observational
Primary Outcome
To evaluate the effect of central airway stabilization on symptoms and quality of life in patients with symptomatic and severe tracheobronchomalacia.
Secondary Outcome
To evaluate the effect of central airway stabilization on lung function, exercise capacity and functional status.
Condition
Tracheomalacia
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
150
Start Date
January 2002
Completion Date
March 2010
Primary Completion Date
March 2010
Eligibility Criteria
Inclusion Criteria: - Suspicion of symptomatic tracheal and/or bronchial collapse during bronchoscopy or Dynamic Computed Tomographic study. - Chronic Obstructive Pulmonary Disease (regardless of severity) and suspicion of tracheal and/or bronchial collapse Exclusion Criteria: - inability to follow commands - Focal extrinsic compression of the trachea/bronchi by mass or other
Gender
All
Ages
21 Years - N/A
Accepts Healthy Volunteers
No
Contacts
Armin Ernst, M.D. FCCP, ,
Location Countries
United States
Location Countries
United States
Administrative Informations
NCT ID
NCT00550602
Organization ID
2005P000112
Study Sponsor
Beth Israel Deaconess Medical Center
Study Sponsor
Armin Ernst, M.D. FCCP, Principal Investigator, Beth Israel Deaconess Medical Center
Verification Date
April 2010