Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment

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Brief Title

Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment

Official Title

Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment

Brief Summary

      The purpose of this study is to investigate the effects of chronic elevated levels of
      Prolactin on metabolism and insulin sensitivity by studying patients with hyperprolactinemia
      before and after treatment.
    



Study Type

Observational


Primary Outcome

Insulin sensitivity

Secondary Outcome

 QoL, body composition, intrahepatic and intramyocellular fat, substrate metabolism, glucose tolerance

Condition

Hyperprolactinemia

Intervention

Cabergoline

Study Arms / Comparison Groups

 Hyperprolactinemia
Description:  Patients recently diagnosed with hyperprolactinemia

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Other

Estimated Enrollment

0

Start Date

May 2008

Completion Date

November 2016

Primary Completion Date

November 2016

Eligibility Criteria

        Inclusion Criteria:

          -  Written consent

          -  Age between 18 and 70

          -  At diagnose a serum prolactin > 200 microgram/l (10 U/l)

        Exclusion Criteria:

          -  Hypothyroidism

          -  Use of any medication

          -  Pregnancy
      

Gender

All

Ages

18 Years - 70 Years

Accepts Healthy Volunteers

No

Contacts

Jens Otto L. Jørgensen, Professor MD, , 

Location Countries

Denmark

Location Countries

Denmark

Administrative Informations


NCT ID

NCT00699530

Organization ID

MM-ISP-20070132


Responsible Party

Sponsor

Study Sponsor

University of Aarhus

Collaborators

 Aarhus University Hospital

Study Sponsor

Jens Otto L. Jørgensen, Professor MD, Principal Investigator, Aarhus University Hospital, Department of Endocrinology


Verification Date

December 2014