Semitendinosus Graft as Meniscal Transplant

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Brief Title

Semitendinosus Graft as Meniscal Transplant

Official Title

Autologous Semitendinosus Tendon Graft as Meniscal Transplant - a Clinical Pilot Study

Brief Summary

      Removal of meniscal tissue is described to result in poor knee function and a significant
      risk for future development of osteoarthritis. Different implants have been suggested to
      substitute a removed meniscus. Meniscal allograft transplantation is not widely available due
      to costs and availability. The semitendinosus tendon is a known graft with biological
      properties with potential to remodel and revascularize in an intraarticular environment such
      as anterior cruciate ligament reconstruction. The objective for this study was to investigate
      whether the semitendinosus tendon graft could function as a meniscal transplant.

Study Type

Observational

Primary Outcome

Failure

Secondary Outcome

 Improved subjective knee function

Condition

Patient Satisfaction

Intervention

Surgical technique

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status

Procedure

Estimated Enrollment

10

Start Date

January 1, 2018

Completion Date

January 1, 2026

Primary Completion Date

January 1, 2024

Eligibility Criteria

        Inclusion Criteria:

          -  Previous subtotal or total meniscectomy

          -  Post meniscectomy symptoms

          -  No osteoarthritic changes on radiography more than Ahlbäck 1

          -  Knee aligment (hip-knee-angle) +/- 3°

          -  No persisting ACL insufficiency

        Exclusion Criteria:

          -  Difficulty understanding the instructions

          -  Current psychiatric diagnosis

          -  Smoking

Gender

All

Ages

20 Years - 50 Years

Accepts Healthy Volunteers

No

Contacts

, 0046707202646, [email protected]

Location Countries

Sweden

Location Countries

Sweden

Administrative Informations

NCT ID

NCT04753424

Organization ID

semiTmeniscus

Responsible Party

Principal Investigator

Study Sponsor

Karolinska Institutet

Study Sponsor

, ,

Verification Date

June 2022