Comparing Adductor Canal Block and Adductor Canal Block-Local Infiltration Analgesia for Post-operative Pain Management

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Brief Title

Comparing Adductor Canal Block and Adductor Canal Block-Local Infiltration Analgesia for Post-operative Pain Management

Official Title

Comparison of the Effectiveness of Adductor Canal Block Versus Combination of Adductor Canal Block and Local Infiltration Analgesia: A Randomized Controlled Trial of the Effect on Postoperative Analgesia and Motor Power

Brief Summary

      Anterior cruciate ligament (ACL) reconstruction is one of the most commonly performed
      surgeries amongst young orthopedic surgery patients. Optimal post-operative pain control
      helps to reduce the opioid burden and to improve the patient's experience. Regional
      anesthesia, such as the femoral nerve block (FNB) and adductor canal block (ACB), are
      commonly used for post-operative pain control after surgery. The ACB has replaced the FNB.
      This is because the ACB targets the femoral nerve, while avoiding the numbing effects on
      quadricep muscle strength that make it difficult to move the leg. Another form of pain
      control is local infiltration anesthesia (LIA), which directly blocks pain in the knee.
      Similar to the ACB, it avoids the numbing effects on the quadricep muscle.This can help
      improve patient safety and experience by reducing risks of falls and allowing the patient to
      move earlier. This can also be associated with decreased time in the hospital and decreased
      costs. Technically, it is less complex and can be done the shorter period of time.

      The purpose of this study is to refine the pain management technique following anterior
      cruciate ligament surgery. More specifically, the aim of this study is to evaluate the
      effects of LIA alone, and a LIA-ACB combination on post-operative pain and thigh muscle

Study Type


Primary Outcome

Oral morphine equivalent consumption

Secondary Outcome

 inta-operative opioid consumption


ACL Tear


Local Infiltration Anesthetic

Study Arms / Comparison Groups

 Local Infiltration Anesthetic
Description:  This group of patients will receive the local infiltration anesthetic only.


* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status


Estimated Enrollment


Start Date

February 2021

Completion Date

November 2021

Primary Completion Date

August 2021

Eligibility Criteria

        Inclusion Criteria:

          -  English speaking or any other language with possibility of adequate translation

          -  ASA I-III patients

          -  Age 18-50

          -  BMI ≤ 38 kg/m2

        Exclusion Criteria:

          -  Refusal or inability to provide informed consent

          -  Any contraindication to regional anesthesia including coagulopathy or bleeding

          -  Allergy to local anesthetics, or infection at the site of the block

          -  History of long-term opioid intake (more than 3 months use) or chronic pain disorder
             (more than 3 months)

          -  History of preexisting neuropathy in the operative leg

          -  Revision of ACL repair




18 Years - 50 Years

Accepts Healthy Volunteers



, 613-737-8899, [email protected]

Administrative Informations



Organization ID


Responsible Party


Study Sponsor

Ottawa Hospital Research Institute

Study Sponsor

, , 

Verification Date

January 2021