Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos

Brief Title

Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos

Official Title

Transfer of Aneuploid or Mosaic Embryos Following Preimplantation Genetic Testing

Brief Summary

      To determine how often embryos reported to be abnormal by preimplantation genetic testing
      result in liveborn infants. To evaluate whether the pregnancies that result from these
      embryos are higher risk for complications and whether the resulting babies have higher risk
      for health or developmental issues in the first five years after birth.
    



Study Type

Interventional


Primary Outcome

Pregnancy Rate

Secondary Outcome

 Live birth rate

Condition

Aneuploidy

Intervention

Non-euploid embryo transfer

Study Arms / Comparison Groups

 Non-euploid Transfer
Description:  Patients desiring pregnancy who have no acceptable euploid embryos available for transfer who chose to undergo embryo transfer of a non-euploid embryo (either aneuploid or mosaic).

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Other

Estimated Enrollment

300

Start Date

April 11, 2019

Completion Date

April 1, 2029

Primary Completion Date

April 2025

Eligibility Criteria

        Inclusion Criteria:

          -  Available aneuploid or mosaic embryos

          -  No acceptable euploid embryos available

          -  Willing to travel to Stanford for treatment

          -  English language fluency

        Exclusion Criteria:

          -  Use of gestational carrier

          -  Living outside the United States
      

Gender

Female

Ages

18 Years - 55 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Ruth Lathi, MD, (408)688-9749, [email protected]

Location Countries

United States

Location Countries

United States

Administrative Informations


NCT ID

NCT04109846

Organization ID

IRB-46420


Responsible Party

Principal Investigator

Study Sponsor

Stanford University


Study Sponsor

Ruth Lathi, MD, Principal Investigator, Stanford University


Verification Date

March 2021