Optimized Characterization of Takotsubo Syndrome by Obtaining Pressure Volume Loops

Brief Title

Optimized Characterization of Takotsubo Syndrome by Obtaining Pressure Volume Loops

Official Title

Optimized Characterization of Takotsubo Syndrome by Obtaining Pressure Volume Loops

Brief Summary

      Aim of this prospective study is to assess the pathophysiology of Takotsubo Syndrome by
      obtaining pressure volume loops with conductance catheters, which allows detailed conclusions
      regarding systolic and diastolic hemondynamics and subsequently regarding potential
      underlying mechanisms
    



Study Type

Interventional


Primary Outcome

Changes in contractility derived from pressure-volume measurements

Secondary Outcome

 Energetic parameters derived from pressure-volume measurements

Condition

Takotsubo Syndrome

Intervention

Measurements of left ventricular pressure and volume


Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Diagnostic Test

Estimated Enrollment

25

Start Date

September 1, 2017

Completion Date

December 2022

Primary Completion Date

December 2022

Eligibility Criteria

        Inclusion Criteria:

          -  Confirmed Takotsubo syndrome according to current diagnostic criteria including
             complete normalization of left ventricular function during follow-up

          -  Sinus rhythm during invasive measurements

          -  Age ≥18 years

          -  Written informed consent

        Exclusion Criteria:

          -  Cardiogenic shock

          -  Signs of myocarditis or myocardial infarction with spontaneous lysis of thrombus in
             cardiac magnetic resonance imaging

          -  Pregnancy

          -  Participation in another trial
      

Gender

All

Ages

18 Years - N/A

Accepts Healthy Volunteers

No

Contacts

, +49 451 500 44501, [email protected]

Location Countries

Germany

Location Countries

Germany

Administrative Informations


NCT ID

NCT03726528

Organization ID

17-078


Responsible Party

Principal Investigator

Study Sponsor

University of Luebeck


Study Sponsor

, , 


Verification Date

May 2021