Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology

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Brief Title

Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology

Official Title

Efficacy Study of Shunt Operation in Patients With Disorder of Consciousness of Post-traumatic Hydrocephalus (PTH) by Methods of Neuroelectrophysiology

Brief Summary

      The symptoms of hydrocephalus containing consciousness condition with muscle tone in some
      patients will be relieved, after the cerebrospinal fluid release test is carried out.
      Neuroelectrophysiology in patients with disorders of consciousness of post-traumatic
      hydrocephalus (PTH) can establish the association with consciousness and muscle tone to a
      certain extent, and predict the shunt effect of PTH with disorders of consciousness.
    



Study Type

Observational


Primary Outcome

Score of glasgow outcome scale in 6 months after shunt operation

Secondary Outcome

 Score of glasgow outcome scale in 6 months after shunting under different ventricular pressure

Condition

Hydrocephalus



Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information



Estimated Enrollment

65

Start Date

May 10, 2020

Completion Date

December 31, 2022

Primary Completion Date

December 31, 2022

Eligibility Criteria

        Inclusion Criteria:

        Patients with disorder of consciousness in traumatic brain injury. The presence of
        hydrocephalus through image examination.

        Exclusion Criteria:

        Patients who cannot tolerate shunt surgery. Sedation maintained by greater than
        0.15mg/kg/hour of midazolam or the infusion dose of propofol higher than 4mg/kg/hour.

        Patients who are participating in drug research or other clinical trials.
      

Gender

All

Ages

16 Years - 70 Years

Accepts Healthy Volunteers

No

Contacts

, 15575874018, [email protected]

Location Countries

United States

Location Countries

United States

Administrative Informations


NCT ID

NCT04363658

Organization ID

202001015


Responsible Party

Sponsor

Study Sponsor

Xiangya Hospital of Central South University


Study Sponsor

, , 


Verification Date

May 2020