Association of Hb F Level With Clinical Severity of Beta Thalassemia

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Brief Title

Association of Hb F Level With Clinical Severity of Beta Thalassemia

Official Title

Association of Hb F Level With Clinical Severity of Beta Thalassemia

Brief Summary

      The production of Hb F after birth is an important factor in modifying the clinical severity
      of beta thalassemia because an increased gamma-globin level will bind the additional a-globin
      and form Hb F. The objective of this project is to evaluate the association of Hb F level
      with phenotypic diversity of patients with beta thalassemia.
    



Study Type

Observational


Primary Outcome

Hb F level and severity of anemia


Condition

Beta Thalassemia

Intervention

Hematological Phenotype Analysis

Study Arms / Comparison Groups

 beta thalassemia patients
Description:  

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Diagnostic Test

Estimated Enrollment

1200

Start Date

December 1, 2019

Completion Date

December 30, 2025

Primary Completion Date

December 30, 2024

Eligibility Criteria

        Inclusion Criteria:

          -  Diagnosed with beta-thalassemia

        Exclusion Criteria:

          -  Iron Deficiency Anemia
      

Gender

All

Ages

N/A - N/A

Accepts Healthy Volunteers

No

Contacts

, 02061648293, [email protected]

Location Countries

China

Location Countries

China

Administrative Informations


NCT ID

NCT04917978

Organization ID

HbF-Beta thalassemia


Responsible Party

Sponsor

Study Sponsor

Nanfang Hospital of Southern Medical University

Collaborators

 ZhuHai Hospital

Study Sponsor

, , 


Verification Date

May 2021