Alpha-1 Foundation DNA and Tissue Bank

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Brief Title

Alpha-1 Foundation DNA and Tissue Bank

Official Title

Alpha-1 Foundation DNA and Tissue Bank

Brief Summary

      This is a long-term follow-up banking protocol that collects medical information and tissue
      (blood, liver and lung) samples for future research; use of data and samples for research
      purposes is overseen by the Tissue Bank Advisory Committee; the purpose of the Bank is to
      further research on alpha-1 antitrypsin deficiency.
    

Detailed Description

      Subject participation includes completion of informed consent, medical questionnaire, and
      email authorization. Subjects may provide a blood sample for alpha-1 antitrypsin genotype,
      phenotype and level. Lung and liver tissue may also be provided if available. Subjects may be
      contacted no more often than annually for updated information.

      This project has a certificate of confidentiality from NIH.
    


Study Type

Observational


Primary Outcome

Data and tissue samples


Condition

Alpha 1 Antitrypsin Deficiency



Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information



Estimated Enrollment

5000

Start Date

December 2002

Completion Date

December 2020

Primary Completion Date

December 2020

Eligibility Criteria

        Inclusion Criteria:

          -  all interested individuals may enroll

        Exclusion Criteria:

          -  there are no exclusion criteria
      

Gender

All

Ages

N/A - N/A

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Mark L Brantly, MD, , 

Location Countries

United States

Location Countries

United States

Administrative Informations


NCT ID

NCT00884455

Organization ID

IRB201500842 AATD Tissue Bank


Responsible Party

Sponsor

Study Sponsor

University of Florida

Collaborators

 Alpha-1 Foundation

Study Sponsor

Mark L Brantly, MD, Principal Investigator, University of Florida


Verification Date

June 2019