Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Country Product Indication Sponsor Date
Immune globulin intravenous (human) Juvenile rheumatoid arthritis Immuno Clinical Research Corp.;750 Lexington Avenue;New York, New York, 10022 December 16, 1992
PEG-glucocerebrosidase Gaucher disease National Institute of Mental Health, NIH;49 Convent Dr. MSC4405, Bldg. 49, Room B1EE16;Bethesda, Maryland, 20892 December 9, 1992
Interferon beta-1a (recombinant) Symptomatic patients with AIDS including all patients with CD4 T-cell counts less than 200 cells per mm3 EMD Serono, Inc.;One Technology Place;Roackland, Massachusetts, 02370 December 2, 1992
Idarubicin Chronic myeloid leukemia Pharmacia & Upjohn;7000 Portage Road, Unit 0633-298-113;Kalamazoo, Michigan, 49001 December 2, 1992
Idarubicin Myelodysplastic syndromes Pharmacia & Upjohn;7000 Portage Road, Unit 0633-298-113;Kalamazoo, Michigan, 49001 December 1, 1992
Topiramate Lennox-Gastaut syndrome Johnson & Johnson Pharmaceutical R & D, LLC;Route 202, P.O. Box 300;Raritan, New Jersey, 08869 November 25, 1992
C1-esterase-inhibitor, human, pasteurized Prevention and/or treatment of acute attacks of hereditary angioedema CSL Behring LLC;1020 First Ave., PO Box 61501;King of Prussia, Pennsylvania, 19406 October 16, 1992
Herpes simplex virus gene Primary and metastatic brain tumors Genetic Therapy, Inc.;938 Clopper Road;Gaithersburg, Maryland, 20878 October 16, 1992
Interleukin-1 receptor antagonist, human recombinant Graft Versus Host Disease Swedish Orphan Biovitrum AB (publ) (SOBI);SE-112 76;Stockholm October 16, 1992
Antihemophilic factor/von Willebrand factor complex (human), dried, pasteurized Von Willebrand disease CSL Behring;1020 First Avenue, PO Box 61501;King Of Prussia, Pennsylvania, 19406 October 16, 1992
Allopurinol sodium Tongue neoplasm Catalytica Pharmaceuticals, Inc;PO Box 1887;Greenville, North Carolina, 27835 October 16, 1992
Immune globulin intravenous (human) Polymyositis/dermatomyositis Immuno Clinical Research Corp.;155 East 56th Street;New York, New York, 10022 October 13, 1992
AI-RSA Autoimmune uveitis AutoImmune, Inc.;128 Spring Street;Lexington, Massachusetts, 02173 October 8, 1992
Oxaliplatin Ovarian cancer Debio Pharm S.A.;Rue des Terreaux 17, CH-1000; October 6, 1992
Butyrylcholinesterase Post-surgical apnea Shire Laboratories Inc.;1550 East Gude Drive;Rockville, Maryland, 20850 September 30, 1992
Botulinum toxin type A Synkinetic closure of the eyelid associated with VII cranial nerve aberrant regeneration Botulinum Toxin Research Associates, Inc.;1261 Furnace Brook Parkway;Quincy, Massachusetts, 02169 September 15, 1992
Anaritide acetate Patients with acute renal failure Scios, Inc.;2450 Bayshore Parkway;Mountain View, California, 94043 August 27, 1992
Fialuridine Adjunctive treatment of chronic active hepatitis B Oclassen Pharmaceuticals, Inc.;100 Pelican Way;San Rafael, California, 94901 July 24, 1992
L-threonine Spasticity associated with familial spastic paraparesis Interneuron Pharmaceuticals, Inc.;99 Hayden Ave., Suite 200;Lexington, Massachusetts, 02421 July 24, 1992
Interferon beta-1a (recombinant human) Acute non-A, non-B hepatitis Biogen, Inc.;14 Cambridge Center;Cambridge, Massachusetts, 02142 July 24, 1992
Secretory leukocyte protease inhibitor Bronchopulmonary dysplasia Synergen, Inc.;1885 33rd Street;Boulder, Colorado, 80301 June 30, 1992
Cystic fibrosis gene therapy Cystic fibrosis Genzyme Corporation;One Mountain Rd., P.O. Box 9322;Framingham, Massachusetts, 01701 June 30, 1992
Protein C concentrate For replacement therapy in congenital protein C deficiency for the prevention and treatment of thrombosis, pulmonary emboli, and purpura fulminans Baxalta US, Inc.;One Baxter Way;West Lake Village, California, 91362 June 23, 1992
Minocycline HCl Chronic malignant pleural effusion Lederle Laboratories Division;Division of American Cyanamid Company, 401 N. Middletown Road;Pearl River, New York, 10965 June 19, 1992
Protein C concentrate For replacement therapy in patients with congenital or acquired protein C deficiency for the prevention and treatment of warfarin-induced skin necrosis during oral anticoagulation Immuno Clinical Research Corp.;750 Lexington Avenue;New York, New York, 10022 June 19, 1992