Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Country Product Indication Sponsor Date
Botulinum toxin type B Cervical dystonia Soltice Neurosciences, LLC;4010 Dupont Circle, Suite L-07;Louisville, Kentucky, 40207 January 16, 1992
Cystic fibrosis transmembrane conductance regulator Cystic fibrosis Genzyme Corporation;One Mountain Road, P.O. Box 9322;Framingham, Massachusetts, 01701 January 14, 1992
Dapsone USP For the combination treatment of Pneumocystis carinii pneumonia in conjunction with trimethoprim Jacobus Pharmaceutical Company;37 Cleveland Avenue, P.O. Box 5290;Princeton, New Jersey, 08540 January 8, 1992
Cryptosporidium hyperimmune bovine colostrum IgG concentrate Cryptosporidiosis ImmuCell Corporation;56 Evergreen Drive;Portland, Maine, 04103 December 30, 1991
Dapsone USP Prophylaxis for Pneumocystis carinii pneumonia Jacobus Pharmaceutical Company;37 Cleveland Avenue, P.O. Box 5290;Princeton, New Jersey, 08540 December 24, 1991
Dexrazoxane For the prevention of cardiomyopathy associated with doxorubicin administration Pharmacia & Upjohn;7000 Portage Road;Kalamazoo, Michigan, 49001 December 17, 1991
L-baclofen Spasticity associated with spinal cord injury or multiple sclerosis Osmotica Pharmaceutical Corp.;1205 Culbreth Drive, Suite 200;Wilmington, North Carolina, 28405 December 17, 1991
Baclofen Intractable spasticity due to multiple sclerosis or spinal cord injury Metacel Pharmaceuticals, LLC;137 N. Broad Street, Suite E;Winder, Georgia, 30680 December 16, 1991
Interferon beta-1a Multiple sclerosis Biogen, Inc.;14 Cambridge Center;Cambridge, Massachusetts, 02142 December 16, 1991
Botulinum toxin type A Dynamic muscle contracture in pediatric cerebral palsy patients Allergan, Inc.;2525 Dupont Drive, P.O. Box 19534;Irvine, CA, 92623-9534 December 6, 1991
Botulinum toxin type A Dynamic muscle contracture in pediatric cerebral palsy patients Allergan, Inc.;2525 Dupont Drive, P.O. Box 19534;Irvine, California, 92623 December 6, 1991
Sermorelin acetate AIDS-associated catabolism/weight loss EMD Serono, Inc.;One Technology Place;Rockland, Massachusetts, 02370 December 5, 1991
Matrix metalloproteinase inhibitor Corneal ulcers Glycomed, Inc;860 Atlantic Avenue;Alameda, California, 94501 December 5, 1991
Amphotericin B lipid complex Invasive fungal infections Liposome Company, Inc.;One Research Way;Princeton, New Jersey, 08540 December 5, 1991
Liposome encapsulated recombinant interleukin-2 Brain and CNS tumors Oncothyreon Canada, Inc.;2011-94 St., NW, Suite 200; November 25, 1991
Monoclonal antibody to cytomegalovirus (human) Cytomegalovirus retinitis in patients with AIDS Protein Design Labs, Inc.;2375 Garcia Avenue;Mountain View, California, 94043 November 15, 1991
Somatropin for injection AIDS-associated catabolism/weight loss EMD Serono, Inc.;One Technology Place;Roackland, Massachusetts, 02370 November 15, 1991
Imiglucerase Replacement therapy in patients with types I, II, and III Gaucher's disease Genzyme Corporation;One Kendall Square;Cambridge, Massachusetts, 02139 November 5, 1991
Halofantrine Malaria SmithKline Beecham Pharmaceuticals;One Franklin Plaza, P.O. Box 7929;Philadelphia, Pennsylvania, 19101 November 4, 1991
Pramiracetam Sulfate For the management of cognitive dysfunction and enhancement of antidepressant activity associated with electroconvulsive therapy Cambridge Neuroscience, Inc.;1 Kendall Square, Bldg. 700;Cambridge, Massachusetts, 02139 November 4, 1991
Botulinum toxin type F Spasmodic torticollis (cervical dystonia) Ipsen Limited;27 Maple Street;Milford, Massachusetts, 01757 October 24, 1991
Synthetic derivative of 16-hydroxy-9Z, 12Z, 14E-octadecatrienoic acid Prophylactic treatment of sickle cell disease Omex International, Inc.;6001 Savoy, Suite 110;Houston, Texas, 77036 October 24, 1991
Metronidazole Perioral dermatitis Galderma Laboratories, Inc.;P.O. Box 331329;Fort Worth, Texas, 76163 October 24, 1991
Dynamine Charcot-Marie-Tooth disease Mayo Foundation;200 First Street Southwest;Rochester, Minnesota, 55905 October 16, 1991
Lodoxamide tromethamine Vernal keratoconjunctivitis Alcon Laboratories, Inc.;6201 South Freeway;Fort Worth, Texas, 76134 October 16, 1991