Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Country Product Indication Sponsor Date
Obatoclax mesylate Myelodysplastic syndrome Gemin X, Inc.;400 Chesterfield Parkway, Suite 100;Malvern, Pennsylvania, 19355 November 6, 2006
Estradiol Gel Estrogen replacement therapy in females with Turner syndrome Ascend Therapeutics US, LLC;607 Herndon Parkway, Suite 110;Herndon, Virginia, 21070 October 31, 2006
Chimeric monoclonal antibody to mesothelin Pancreatic Cancer Morphotek, Inc.;210 Welsh Pool Road;Exton, Pennsylvania, 19341 October 31, 2006
R-(-)-gossypol Chronic lymphocytic leukemia Ascenta Therapeutics, Inc.;101 Lindenwood Drive, Suite 405;Malvern, Pennsylvania, 19355 October 24, 2006
Cysteamine enteric coated Cystinosis Horizon Pharma USA, Inc.;150 S. Saunders Road;Lake Forest, Illinois, 60045 October 24, 2006
Carlumab Pancreatic Cancer Centocor, Inc.;200 Great Valley PArkway;Malvern, Pennsylvania, 19355 October 24, 2006
Adalimumab Pediatric Crohn's disease AbbVie, Inc.;1 N. Waukegan Road, Bldg AP30, Dept. PA77;North Chicago, Illinois, 60064 October 19, 2006
4-(2-fluorophenyl)-6-methyl-2-(1-piperzinyl) Chronic Functional Vomiting to include functional vomiting and cyclic vomiting syndrome Dynogen Pharmaceuticals, Inc.;52 Second Avenue;Waltham, Massachusetts, 02451 October 11, 2006
5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(phenylmethyl)-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S,10S)- (9CI) Malignant gliomas Reata Pharmaceuticals, Inc.;1950 N. Stemmons Freeway;Dallas, Texas, 75207 October 11, 2006
Dovitinib Multiple myeloma Novartis Pharmaceuticals Corporation;One Health Plaza;East Hanover, New Jersey, 07936 October 3, 2006
Coagulation Factor VIIa (Recombinant) Bleeding in patients experiencing intracranial hemorrhage Novo Nordisk, Inc.;P. O. Box 846;Plainsboro, New Jersey, 08536 October 3, 2006
Capsaicin Intermetatarsal neuroma (Morton's Neuroma) that does not respond to conservative treatment and requires either neurectomy or neurolysis Centrexion Corporation;509 S. Exeter Street, Suite 202;Baltimore, Maryland, 21202 September 29, 2006
Sorafenib Metastatic Melanoma Bayer Pharmaceuticals Corp.;100 Bayer Blvd, P. O. Box 915;Whippany, New Jersey, 07981 September 29, 2006
Eflornithine Glioma Orbus Therapeutics, Inc.;1043 Via Tornasol;Aptos, California, 95003 September 29, 2006
Humanized anti-CD3 monoclonal antibody Recent-onset Type I diabetes MacroGenics, Inc.;9640 Medical Center Drive;Rockville, MD, 20850 September 29, 2006
Capsaicin Intermetatarsal neuroma (Morton's Neuroma) that does not respond to conservative treatment and requires either neurectomy or neurolysis Centrexion Corporation;509 S. Exeter Street, Suite 202;Baltimore, Maryland, 21202 September 29, 2006
Teplizumab Recent-onset Type I diabetes MacroGenics, Inc.;9704 Medical Center Drive;Rockville, Maryland, 20850 September 29, 2006
Rabbit anti-human thymocyte globulin (rATG) Induction treatment to prevent rejection and to minimize maintenance immunosupression in pediatric liver transplant recipients Children's Hospital of Pittsburgh;University of Pittsburgh;Pittsburgh, Pennsylvania, 15213 September 26, 2006
Cytomegalovirus DNA Vaccine w/Copolymer/Benzalkonium Chloride Cytomegalovirus retinitis Vical Inc.;10390 Pacific Center Court;San Diego, California, 92121 September 23, 2006
Human monoclonal antibody directed against serotype 011 Pseudomonas aeruginosa Hospital acquired pneumonia caused by serotype 011 positive Pseudomonas aeruginosa Kenta Biotech Limited;Rehhagstrsase; September 18, 2006
Heparin-binding epidermal growth factor-like growth factor Necrotizing enterocolitis Trillium Therapeutics, Inc.;96 Skyway Avenue, M9W 4Y4; September 18, 2006
Synthetic human secretin For use in conjunction with diagnostic procedures (excluding ERCP) for pancreatic disorders to increase pancreatic fluid secretion Innovate Biopharmaceuticals, Inc.;8601 Six Forks Road, Suite 400;Raleigh, North Carolina, 27615 September 18, 2006
2-(3-Diethylaminopropyl)-8,8-dipropyl-2-azaspiro[4,5] decane dimaleate Carcinoid tumors Callisto Pharmaceuticals, Inc.;420 Lexington Avenue;New York, New York, 10170 September 18, 2006
Yttrium (90Y) antiferritin polyclonal antibodies Hodgkin's disease Alissa Pharma, LLC;341 North Woodland St.;Englewood, New Jersey, 07631 September 18, 2006
Melanoma autologous dendritic cell vaccine Metastatic Melanoma Caladrius Biosciences;110 Allen Road, 2nd Floor;Basking Ridge, New Jersey, 07920 September 6, 2006