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Treatments
The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.
You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.
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| Country | Product | Indication | Sponsor | Date |
|---|---|---|---|---|
|
Replication-incompetent GM-CSF-expressing gene-modified allogeneic chronic myeloid leukemia cancer cell lines | Chronic myeloid leukemia | Aduro BioTech, Inc.;740 Heinz Avenue;Berkeley, California, 94710 | April 30, 2010 |
|
Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) | Ovarian cancer | Ortho Biotech;200 Great Valley Parkway;Malvern, Pennsylvania, 19355 | April 30, 2010 |
|
Fingolimod | Chronic inflammatory demyelinating polyneuropathy | Novartis Pharmaceutical Corporation;One Health Plaza;East Hanover, New Jersey, 07936 | April 30, 2010 |
|
Midostaurin | Mastocytosis | Novartis Oncology;One Health Plaza;East Hanover, New Jersey, 07936 | April 30, 2010 |
|
Autologous CD34+ cells transfected with lentiviral vector containing the human WAS cDNA (Telethon 003) | Wiskott Aldrich syndrome | GlaxoSmithKline Intellectual Property Development;980 Great West Road, TW8 9GS England; | April 30, 2010 |
|
Fenretinide | Cystic fibrosis | McGill University;McGill University, Montreal, Quebec, H3A 2T5; | April 7, 2010 |
|
L-ornithine phenylacetate | Hepatic encephalopathy | Ocera Therapeutics, Inc.;5001 South Miami Blvd, Suite 300;Durham, North Carolina, 27703 | April 7, 2010 |
|
N-Acetylmannosamine (ManNAc) | GNE Myopathy (Hereditary Inclusion Body Myopathy Type 2) | National Human Genome Research Institute,NIH;10 Center Drive, Bldg. 10, Room 10C-103;Bethesda, Maryland, 20892 | April 5, 2010 |
|
N-Acetylmannosamine (ManNAc) | Hereditary inclusion body myopathy type 2 | Altamira Bio, Inc. (ABIO);3 Columbus Circle, 15th Floor;New York, NY, 10019 | April 5, 2010 |
|
GNE plasmid(H001) | Hereditary inclusion body myopathy type 2 | HIBM Research Group;18341 Sherman Way #201A;Reseda, California, 91335 | March 26, 2010 |
|
Reversal agent linked to chloroquine-like moiety | Malaria | DesignMedix;2828 SW Corbett Avenue;Portland, Oregon, 97201 | March 26, 2010 |
|
Water-miscible vitamin A palmitate | Bronchopulmonary dysplasia | Fox Pharma, Inc.;6097 Hidden Valley Drive;Doylestown, Pennsylvania, 18902 | March 26, 2010 |
|
Anti-T-lymphocyte immune globulin, rabbit | Graft Versus Host Disease | Neovii Biotech NA, Inc.;430 Bedford Street, Suite 195;Lexington, Massachusetts, 02420 | March 26, 2010 |
|
Fully human anti-interferon gamma monoclonal antibody | Hemophagocytic lymphohistiocytosis | NovImmune S.A.;14 chemin des Aulx; | March 26, 2010 |
|
Recombinant Human soluble Fc-gamma Receptor IIb | Idiopathic thrombocytopenic purpura | Baxalta US Inc., now part of Shire Plc;650 Kendall Street;Cambridge, Massachusetts, 02142 | March 22, 2010 |
|
Chenodiol | Cerebrotendinous xanthomatosis | Retrophin, Inc.;3721 Valley Centre Drive, Suite 200;San Diego, California, 92130 | March 22, 2010 |
|
Recombinant human glutamic acid decarboxylase 65KDa isoform | Type I diabetes with residual beta cell function | Diamyd Therapeutics AB;Linnegatan 89B; | March 22, 2010 |
|
Tirasemtiv | Amyotrophic lateral sclerosis | Cytokinetics Inc.;280 East Grand Avenue;South San Francisco, California, 94080 | March 2, 2010 |
|
Fast skeletal muscle troponin activator | Amyotrophic lateral sclerosis | Cytokinetics Inc.;280 East Grand Avenue;South San Francisco, CA, 94080 | March 2, 2010 |
|
Replication-incompetent GM-CSF-expressing gene-modified allogeneic acute myeloid leukemia cancer cell lines | Acute myeloid leukemia | Aduro BioTech, Inc.;740 Heinz Avenue;Berkeley, California, 94710 | March 2, 2010 |
|
3-(6-(1-(2,2-difluorobenzo[d] [1,3]dioxyl-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid | Cystic fibrosis | Vertex Pharmaceuticals Inc.;130 Waverly Street;Cambridge, Massachusetts, 02139 | March 2, 2010 |
|
Replication-incompetent GM-CSF-expressing gene-modified allogeneic pancreatic cancer cell lines | Pancreatic cancer | Aduro BioTech, Inc.;740 Heinz Avenue;Berkeley, California, 94710 | March 1, 2010 |
|
Allogeneic hematopoietic stem cell | Graft Versus Host Disease | Kiadis Pharma Netherlands B.V.;Entrada 231 - 234; | February 2, 2010 |
|
MA09-hRPE cells | Stargardt's macular dystrophy | Advanced Cell Technology, Inc.;33 Locke Drive, First Floor;Worcester, MA, 01605 | February 2, 2010 |
|
Ciprofloxacin DPI | Cystic fibrosis | Bayer HealthCare Pharmaceuticals, Inc.;100 Bayer Blvd, P. O. Box 915;Whippany, New Jersey, 07981 | February 2, 2010 |
