Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Country Product Indication Sponsor Date
Allopurinol riboside Cutaneous and visceral leishmaniasis Burroughs Wellcome Company;3030 Cornwallis Road, P.O. Box 12700;Research Triangle Park, NC, 27709 December 4, 1985
Allopurinol riboside Leishmaniasis Burroughs Wellcome Company;3030 Cornwallis Road, P.O. Box 12700;Research Triangle Park, North Carolina, 27709 December 4, 1985
Mesna For use as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis Degussa Corporation;65 Challenger Road;Ridgefield Park, New Jersey, 07660 November 14, 1985
Zinc acetate Wilson disease Lemmon Company;1510 Delp Drive;Kulpsville, Pennsylvania, 19443 November 6, 1985
Monoclonal antiendotoxin antibody XMMEn-0e5 Patients with gram-negative sepsis which has progressed to shock Pfizer, Inc.;235 East 42nd Street;New York, New York, 10017 November 4, 1985
Ganciclovir sodium Cytomegalovirus retinitis in immunocompromised patients with AIDS Syntex (USA), Inc.;3401 Hillview Avenue;Palo Alto, California, 94304 October 31, 1985
Tranexamic acid Patients with congenital coagulopathies who are undergoing surgical procedures (e.g. dental extractions). Pharmacia Inc.;P.O. Box 16529;Columbus, OH, 43216 October 29, 1985
Methotrexate sodium Pediatric osteosarcoma Lederle Laboratories;Division of American Cyanamid Company, 401 N. Middletown Road;Pearl River, New York, 10965 October 21, 1985
Hydroxycobalamin/sodium thiosulfate Severe acute cyanide poisoning Hall, Alan H., M.D.;Mile 5.0 Pass Creek Road, PO Box 24;Elk Mountain, Wyoming, 82324 October 4, 1985
Epoprostenol Pulmonary Arterial Hypertension Glaxo Wellcome Inc.;5 Moore Drive;Research Triangle Park, North Carolina, 27709 September 25, 1985
Rifampin, isoniazid, pyrazinamide For the short-course treatment of tuberculosis Hoechst Marion Roussel;P.O. Box 9627;Kansas City, Missouri, 64134 September 12, 1985
Tranexamic acid Hereditary angioneurotic edema Pharmacia Inc.;P.O. Box 16529;Columbus, Ohio, 43216 September 9, 1985
Pentastarch As an adjunct in leukapheresis to improve the harvesting and increase the yield of leukocytes by centrifugal means DuPont Pharmaceuticals;E.I. Du Pont De Nemours & Co.;Wilmington, Delaware, 19898 August 28, 1985
Ifosfamide Soft tissue sarcomas Bristol-Myers Squibb Company;P.O. Box 4000, Mail Stop D12-02;Princeton, New Jersey, 08543 August 7, 1985
Pentosan polysulfate sodium Interstitial cystitis Alza Corporation;950 Page Mill Rd., PO Box 10950;Palo Alto, California, 94303 August 7, 1985
Ifosfamide Bone sarcomas Bristol-Myers Squibb Company;P.O. Box 4000, Mail Stop D12-02;Princeton, NJ, 08543-4000 August 7, 1985
Ifosfamide Soft tissue sarcomas Bristol-Myers Squibb Pharmaceutical Research Institute;P.O. Box 4000;Princeton, NJ, 08543 August 7, 1985
Trimetrexate glucuronate Metastatic colorectal adenocarcinoma Medimmune Oncology, Inc.;One MedImmune Way;Gaithersburg, MD, 20878 July 25, 1985
Trimetrexate glucuronate Metastatic carcinoma of the head and neck (i.e. buccal cavity, pharynx, and larynx). Medimmune Oncology, Inc.;One MedImmune Way;Gaithersburg, MD, 20878 July 25, 1985
Trimetrexate glucuronate Pancreatic adenocarcinoma Medimmune Oncology, Inc.;One MedImmune Way;Gaithersburg, Maryland, 20878 July 25, 1985
Cromolyn sodium 4% ophthalmic solution Vernal keratoconjunctivitis Fisons Corporation;755 Jefferson Rd., P.O. Box 1710;Rochester, New York, 14603 July 24, 1985
Ammonium 21-tungsto-9-antimoniate Acquired immunodeficiency syndrome Rhone-Poulenc Rorer Pharm.;500 Arcola Road;Collegeville, Pennsylvania, 19426 July 17, 1985
Zidovudine AIDS related complex Glaxo Wellcome Inc.;5 Moore Drive;Research Triangle Park, NC, 27709 July 17, 1985
Defibrotide Thrombotic thrombocytopenic purpura Crinos International;Via Belvedere 1;Villa Guardia, Italy, 22079 July 5, 1985
Antithrombin III (human) concentrate IV For prophylaxis and treatment of thromboembolic episodes in patients with genetic AT-III deficiency CSL Behring;1020 First Ave., PO Box 61501;King of Prussia, Pennsylvania, 19406 July 2, 1985