Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

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Country Product Indication Sponsor Date
Eflornithine HCl African trypanosomiasis Hoechst Marion Roussel;P.O. Box 9627;Kansas City, Missouri, 64134 April 23, 1986
Eflornithine HCl Pneumocystis carinii pneumonia in AIDS patients Marion Merrell Dow, Inc.;P.O. Box 9627;Kansas City, Missouri, 64134 April 18, 1986
Epoetin alfa Anemia associated with end stage renal disease Amgen, Inc.;1840 Dehavilland Drive;Thousand Oaks, California, 91320 April 10, 1986
Diethyldithiocarbamate AIDS Connaught Laboratories;Route 611, P.O. Box 187;Swiftwater, Pennsylvania, 18370 April 3, 1986
Etidronate disodium Hypercalcemia of malignancy inadequately managed by dietary modification and/or oral hydration MGI Pharma, Inc.;5775 West Old Shakopee Rd., Suite 100;Bloomington, Minnesota, 55437 March 21, 1986
Terlipressin Bleeding esophageal varices Ferring Pharmaceuticals Inc.;100 Interpace Parkway;Parsippany-Troy Hills, New Jersey, 07054 March 6, 1986
Potassium citrate and citric acid For the dissolution and control of uric acid and cysteine calculi in the urinary tract Willen Drug Company;; February 14, 1986
Beractant Neonatal respiratory distress syndrome Ross Laboratories;625 Cleveland Avenue;Columbus, OH, 43215 February 5, 1986
Beractant Prevention of neonatal respiratory distress syndrome Ross Laboratories;625 Cleveland Avenue;Columbus, OH, 43215 February 5, 1986
Beractant Respiratory distress syndrome, infant Ross Laboratories;625 Cleveland Avenue;Columbus, Ohio, 43215 February 5, 1986
Anti pan T lymphocyte monoclonal antibody 1. For ex-vivo treatment to eliminate mature T cells from potential bone marrow grafts 2. For in-vivo treatment of bone marrow recipients to prevent graft rejection and graft versus host disease. Xoma Corporation;2910 Seventh Street;Berkeley, California, 94710 January 29, 1986
Anti pan T lymphocyte monoclonal antibody For in-vivo treatment of bone marrow recipients to prevent graft rejection and graft versus host disease Xoma Corporation;2910 Seventh Street;Berkeley, CA, 94710 January 29, 1986
Anti pan T lymphocyte monoclonal antibody For ex-vivo treatment to eliminate mature T cells from potential bone marrow grafts Xoma Corporation;2910 Seventh Street;Berkeley, CA, 94710 January 29, 1986
Benzoate and phenylacetate For adjunctive therapy in the prevention and treatment of hyperammonemia in patients with urea cycle enzymopathy due to carbamylphosphate synthetase, ornithine, transcarbamylase, or argininosuccinate synthetase deficiency ImmunexImmunex;2525 McGaw Avenue, P.O. Box 19791;Irvine, California, 92623 January 21, 1986
Tiopronin Prevention of cystine nephrolithiasis in patients with homozygous cystinuria Pak, Charles Y.C. M.D.;The University of Texas Health Scienc Center at Da, 5323 Harry Hines Boulevard;Dallas, Texas, 75235 January 17, 1986
Flunarizine Alternating hemiplegia of childhood Janssen Research Foundation;P.O. Box 200;Titusville, New Jersey, 08560 January 6, 1986
Flunarizine Alternating hemiplegia Janssen Research Foundation;P.O. Box 200;Titusville, NJ, 08560 January 6, 1986
Guanethidine monosulfate Moderate to severe reflex sympathetic dystrophy and causalgia Novartis Pharmaceuticals Corporation;59 Route 10;East Hanover, New Jersey, 07936 January 6, 1986
Antithrombin III human Preventing or arresting episodes of thrombosis in patients with congenital AT-III deficiency and/or to prevent the occurrence of thrombosis in patients with AT-III deficiency who have undergone trauma or who are about to undergo surgery or parturition American National Red Cross;9312 Old Georgetown Road;Bethesda, Maryland, 20814 January 2, 1986
Somatrem for injection Short stature associated with Turner's syndrome Genentech, Inc.;460 Point San Bruno Boulevard;South San Francisco, CA, 94080 December 9, 1985
Somatrem for injection For long-term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion Genentech, Inc.;460 Point San Bruno Boulevard;South San Francisco, CA, 94080 December 9, 1985
Colchicine For arresting the progression of neurologic disability caused by chronic progressive multiple sclerosis Pharmacontrol Corporation;661 Palisade Ave., P.O. Box 931;Englewood Cliffs, New Jersey, 07632 December 9, 1985
Rifampin For antituberculosis treatment where use of the oral form of the drug is not feasible Hoechst Marion Roussel;P.O. Box 9627;Kansas City, Missouri, 64134 December 9, 1985
Somatrem for injection SHORT syndrome Genentech, Inc.;1 DNA Way;South San Francisco, California, 94080 December 9, 1985
Allopurinol riboside Chagas' disease Burroughs Wellcome Company;3030 Cornwallis Road, P.O. Box 12700;Research Triangle Park, NC, 27709 December 4, 1985