Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Country Product Indication Sponsor Date
Antisense 20-mer oligonucleotide complementary to R2 component of ribonucleotide reductase mRNA Acute myeloid leukemia Lorus Therapeutics, Inc.;2 Meridan Road;M9W 4Z7 April 15, 2005
Anatibant Patients having experienced a severe traumatic brain injury (Glasgow Coma Scale 3 to 8) in order to decrease early mortality and improve long-term functional and neurological outcome Xytis, Inc.;400 South El Camino Real, Suite 1200;San Mateo, California, 94402 April 15, 2005
Tilarginine acetate Cardiogenic shock Arginox Pharmceuticals, Inc.;120 Constitution Drive;Menlo Park, California, 94025 April 11, 2005
2-methoxyestradiol Pulmonary Arterial Hypertension PR Pharmaceuticals, Inc.;1716 Heath Parkway;Fort Collins, Colorado, 80524 April 11, 2005
Human alpha 2,6 sialyltransferase adenoviral gene therapy Patients with invasive (malignant) brain and central nervous system tumors lacking alpha 2,6 sialyltransferase Falk Center for Molecular Therapeutics;1801 Maple Avenue, Suite 4300;Evanston, Illinois, 60201 April 4, 2005
Interleukin-1 Trap Still’s disease Regeneron Pharmaceuticals, Inc.;777 Old Saw Mill River Road;Tarrytown, New York, 10591 April 4, 2005
Troxacitabine Acute myeloid leukemia Structural GenomiX, Inc. (SGX);10505 Roselle Street;San Diego, California, 92121 April 4, 2005
2-methoxyestradiol Ovarian cancer EntreMed, Inc.;4819 Emperor Blvd, Suite 400;Durham, North Carolina, 27703 April 4, 2005
DNA plasmid vector expressing human IL-12 gene Ovarian cancer Celsion Corporation;997 Lenox Drive, Suite 100;Lawrenceville, New Jersey, 08068 April 4, 2005
Melanoma peptide vaccine Metastatic Melanoma Bristol-Myers Squibb Research Inst;5 Research Parkway, P. O. Box 5100;Wallingford, Connecticut, 06492 March 29, 2005
Aminosidine Leishmaniasis The Institute for One World Health;50 California Street, Suite 500;San Francisco, California, 94111 March 29, 2005
Plasmid DNA vector expressing cystic fibrosis transmembrane gene Cystic fibrosis Copernicus Therapeutics, Inc.;11000 Cedar Avenue;Cleveland, Ohio, 44106 March 29, 2005
Arimoclomol Amyotrophic lateral sclerosis Orphazyme ApS;3 Ole Maal�es Vej;Copenhagen March 29, 2005
Adalimumab Juvenile rheumatoid arthritis AbbVie Inc.;1 North Waukegan Road;North Chicago, Illinois, 60064 March 21, 2005
Doxorubicin PIHCA nanoparticles Hepatocellular Carcinoma BioAlliance Pharma;59, Bd Gal Martial Valin - 75015;Paris March 14, 2005
Doxorubicin nanoparticles Hepatocellular Carcinoma Onxeo SA;49 Boulevard du general Martial Valin, 75015;Paris March 14, 2005
Cholest-4-en-3-one, oxime Spinal muscular atrophy Roche Registration Limited March 10, 2005
Sodium aluminosilicate Hepatic encephalopathy Castle Creek Pharmaceuticals LLC;1033 Skokie Blvd, Suite 600;Northbrook, Illinois, 60062 March 4, 2005
Arsenic trioxide Glioma Teva Branded Pharmaceutical Products R&D;, Inc.;41 Moores Road, P. O. Box 4011;Frazer, Pennsylvania, 19355 March 4, 2005
Stem and progenitor cells derived from ex vivo expanded allogeneic umbilical cord blood For use as hematopoietic support in patients with relapsed or refractory hematologic malignancies who are receiving high-dose therapy Gamida Cell Ltd - Teva Joint Venture;5, Nahum Hafzadi St., P. O. Box 34670;Jerusalem March 4, 2005
C-myb antisense oligodeoxynucleotide Chronic myeloid leukemia Genta, Inc.;Two Conell Drive;Berkeley Heights, New Jersey, 07922 February 22, 2005
Aviptadil Pulmonary Arterial Hypertension Mondobiotech Laboratories AG;Herrengasse 21, Furstentum Liechtenstein; February 22, 2005
Nitric oxide Sarcoidosis SensorMedics Corporation;22705 Savi Ranch Parkway;Yorba Linda, California, 92887 February 16, 2005
Recombinant human anti-GDF-8 (growth and differentiation factor-8) antibody Duchenne and Becker muscular dystrophies Wyeth Pharmaceuticals, Inc.;P. O. Box 8299;Philadelphia, Pennsylvania, 19101 February 16, 2005
Mannitol Cystic fibrosis Pharmaxis Ltd.;10 Rodborough Rd.;NSW 2086 February 11, 2005