Published Date: June 26, 2023

Full Text Article


Authors: Miguel Gonçalves Afonso, João Heitor Marques, Sérgio Monteiro, Miguel Lume, Ana Carolina Abreu, Sofia Maia

Retin Cases Brief Rep. 2023 Jul 1;17(4):438-440. doi: 10.1097/ICB.0000000000001222.


PURPOSE: To report a case of acute macular neuroretinopathy (AMN) following SARS-CoV-2 vaccination.

METHODS: Case report.

RESULTS: An otherwise healthy 28-year-old white woman presented to an ophthalmology department with complaints of black paracentral vision scotomata on both eyes that appeared 2 days after receiving the first dose of Vaxzevria vaccine. Fundus examination revealed bilateral red brown petaloid lesions around the fovea. On spectral domain optical coherence tomography, a hyperreflective plaque between the outer plexiform and outer nuclear layers along with disruption of ellipsoid zone/interdigitation zone was observed. A diagnosis of AMN was made.

CONCLUSION: AMN may be an extremely rare adverse event of SARS-COV-2 vaccination, especially in patients with other risk factors.

SYNOPSIS: An otherwise healthy 28-year-old white woman was diagnosed with AMN 2 days after SARS-CoV-2 vaccination.

PMID: 37364205DOI: 10.1097/ICB.0000000000001222