Published Date: May 26, 2023

Full Text Article

Acute posterior multifocal placoid pigment epitheliopathy, serpiginous choroiditis and related diseases

Authors: F Hoogewoud, Y Guex-Crosier, É Bousquet

J Fr Ophtalmol. 2023 Jun;46(6):646-657. doi: 10.1016/j.jfo.2023.03.003. Epub 2023 May 24.


Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) and serpiginous choroiditis are two diseases classified as "white spot syndromes." Both are inflammatory/autoimmune diseases with suspected primary involvement of the choriocapillaris. The former usually has an excellent prognosis, while the latter can rapidly induce legal blindness. Whereas these diseases are well defined and well known, other entities (such as persistent placoid maculopathy or ampiginous choroiditis) with features of both APMPPE and serpiginous choroiditis have been described more recently. This review aims to describe demographic characteristics and multimodal imaging features to help differentiate between these four diseases.

PMID: 37236884DOI: 10.1016/j.jfo.2023.03.003