Published Date: January 16, 2023

Full Text Article

Clinical manifestations of Rickettsia rickettsii in a familial outbreak in Panama

Authors: Carlos A Daza T, Dora Estripeaut, Melissa Santana Morales, Abdiel Rodríguez Sánchez, Aurelio González, Michelle Hernández, Yamitzel Zaldívar, Ámbar Poveda, Mabel Martínez-Monter, Erin Guenther, Nathan Gundacker, Jose Antonio Suarez

Travel Med Infect Dis. 2023 Mar-Apr;52:102542. doi: 10.1016/j.tmaid.2023.102542. Epub 2023 Jan 13.


We report an isolated outbreak of Rickettsia rickettsii in the Ngäbe-Buglé indigenous region, located 750 m (tropical wet) above sea level, in a jungle and mountainous area of Western Panama. Seven members of a family were infected simultaneously, resulting in four deaths. Family outbreaks have been previously described and are responsible for 4-8% of the cases described [1-4]. The simultaneous onset of symptoms in the affected population group is extremely unusual [1,5], but it should not dissuade the clinician from considering the possibility of Rickettsia rickettsii infection.

PMID: 36646398DOI: 10.1016/j.tmaid.2023.102542