Researchers have analysed image and genomic data from the UK Biobank to find insights into rare diseases of the human eye. These include retinal dystrophies – a group of inherited disorders affecting the retina – which are also the leading cause of blindness certification in working-age adults. The retina is...
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South San Francisco, Calif. – A new study in BMC Pregnancy and Childbirth finds that objective information about risk of preeclampsia could be key to driving patient behavior change and creates motivation among pregnant patients to follow provider recommendations on prevention, even among those who are medication-hesitant. Key findings...
Klosterneuburg, Austria – At school, he was inspired by Schrödinger´s book ‘What is Life?’. Now, several decades later, Leonid Sazanov is awarded the Erwin Schrödinger Prize by the Austrian Academy of Sciences (ÖAW). The scientist heads a research group at the Institute of Science and Technology Austria (ISTA) and was...
PARIS, France – For children and adults with Gaucher disease type 1 who are clinically stable on enzyme replacement treatment (ERT), spacing treatment to every three to four weeks appears to work as well as the usual every-two-week schedule, according to a study using data from France. Because spacing treatment also reduced the...
Weifang, China – Light therapy leads to significant improvements in sleep and psycho-behavioral symptoms for patients with Alzheimer’s disease, according to a new study published this week in the open-access journal PLOS ONE by Qinghui Meng of Weifang Medical University, China, and colleagues. The cognitive decline associated with Alzheimer’s disease...
Washington, D.C – Many neurodegenerative diseases, including Alzheimer’s and Parkinson’s, are difficult to diagnose before symptoms begin to appear. However, disease-related biomarkers such as aggregated proteins called amyloids could provide important insight much earlier, if they can be readily detected. Researchers publishing in ACS Sensors have developed one such method...
BASKING RIDGE, N.J. — Lisata Therapeutics, Inc., a clinical-stage pharmaceutical company developing innovative therapies for the treatment of advanced solid tumors and other serious diseases, today announced the publication of a case report detailing a complete response in a patient with metastatic gastroesophageal adenocarcinoma patient treated with LSTA1 in combination...
BASKING RIDGE, N.J. — Lisata Therapeutics, Inc., a clinical-stage pharmaceutical company developing innovative therapies for the treatment of advanced solid tumors and other serious diseases, today announced treatment of the first patient in a Phase 2a trial evaluating LSTA1 in patients with newly diagnosed glioblastoma multiforme (“GBM”). The trial is...
LncRNA DLGAP1-AS2 is overexpressed in patients with non-small cell lung cancer (NSCLC) and may promote cell proliferation by upregulating cyclin D1 by sponging miR-503, according to a study published in BMC Pulmonary Medicine. Effective targets for lung cancer remain lacking. However, it has been suggested that lncRNAs and miRNAs are promising...
LEXINGTON, Mass. – LogicBio Therapeutics, Inc. (Nasdaq:LOGC), a clinical-stage genetic medicine company pioneering gene delivery and gene editing platforms to address rare and serious diseases from infancy through adulthood, today announced results from a retrospective study of the disease course in pediatric patients living with severe methylmalonic acidemia (MMA) caused...