Berlin – Hodgkin’s lymphoma is one of the most common types of lymphoma in young adults. It is characterized by the presence of enlarged B lymphocytes, which are unusual in that they bear on their surface the identifying markers of many other immune cells – such as those found on...
research News
St. Paul MN – Some of the things seven-year-old Holli loves about school are getting candy on her birthday, math (she could do math all day!), and playing on the swings during recess. Her specialized paraprofessional, Mr. Tyler, joins her in swinging and in hallway banter as they navigate Holli’s...
Melbourne, Australia – Researchers, led by University of Melbourne’s Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at the Peter Doherty Institute of Infection and Immunity (Doherty Institute), discovered distinct mechanisms controlling different types of immune cells, and found that, by precisely targeting these mechanisms, they could selectively...
SHANGHAI, China — Hope Medicine Inc. , a clinical-stage innovative biopharmaceutical company, announced recently that the company has completed a Phase Ib study, “An Open-Label Study, to Evaluate Safety, Tolerability, and Efficacy in Male and Female with Androgenetic Alopecia Treated with HMI-115 over a 24-Week Treatment Period”. This study is...
New York, NY – A new study led by researchers at Hospital for Special Surgery (HSS) suggests that currently available therapies may help control chronic muscle inflammation in Duchenne muscular dystrophy (DMD), a severe condition that leads to muscle weakness and premature death. The study, published in PNAS, identifies new...
L-Asparaginase is one of the key drugs used to treat children with acute lymphoblastic leukemia (ALL). However, some children fail to achieve therapeutic levels of L-asparaginase after receiving the drug. The mechanisms underlying such therapeutic failure are not well defined. But now, Vaskar Saha and colleagues, at the Paterson Institute...
Cambridge, Mass. – A rare but potent genetic mutation that alters a protein in the brain’s immune cells, known as microglia, can give people as much as a three-fold greater risk of developing Alzheimer’s disease. A new study by researchers in The Picower Institute for Learning and Memory at MIT...
San Francisco, CA – For Paul Bresge, getting into biotech wasn’t fulfilling a career goal. It was fulfilling a promise. One of his daughters, Tamar, was diagnosed with retinitis pigmentosa in 2010 at the age of 15, when the family was living in Toronto. “We were basically told—in the whole...
NEW YORK – A Ludwig Cancer Research study has found that the circadian clock—which synchronizes physiological and cellular activities with the day-night cycle and is generally thought to be tumor suppressive—in fact has a contextually variable role in cancer. “A lot of evidence suggests that the biological clock is broken...
Collectively rare diseases are anything but rare – they impact 30 million people in the US and ten times that amount globally. And 1 in 3 children suffering from a rare disease will not survive beyond the age of five. One of the biggest challenges facing clinicians is making a...