New York, NY – MSK multiple myeloma specialist Sham Mailankody, MBBS has led trials showing that CAR T cell therapy targeting an antigen called GPRC5D appears to be safe and effective against the disease. Results published in the New England Journal of Medicine in September 2022 showed that 71% of patients responded to the GPRC5D-directed...
research News
NEW ORLEANS, Louisiana – During cold and flu season, excess mucus is a common, unpleasant symptom of illness, but the slippery substance is essential to human health. To better understand its many roles, researchers synthesized the major component of mucus, the sugar-coated proteins called mucins, and discovered that changing the...
Montreal, Canada – A McGill-led team of researchers have made an important discovery shedding light on the genetic basis of a rare skeletal disorder. The study, published in Nature Communications, reveals that a defect in a specific gene (heterozygous variants in the matrix Gla protein, or MGP) may cause a...
Göteborg, Sweden – Disrupted function of “cleaning cells” in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study from the University of Gothenburg describes this newly discovered mechanism. It is well known that obesity increases the risk of...
SHANGHAI, China — Dizal Pharmaceutical today announced that the results of a phase 2 pivotal study of sunvozertinib for the treatment of platinum-pretreated non-small-cell lung cancer (NSCLC) patients with EGFR exon 20 insertion mutations (exon20ins) (WU-KONG6) were published in the peer-reviewed journal The Lancet Respiratory Medicine. The publication of these...
Heidelberg, Germany – Medulloblastoma is one of the most common malignant tumors of the central nervous system (CNS) in children and adolescents. It develops in the area of the cerebellum, which is responsible for movement coordination, among other things. Medulloblastomas enlarge rapidly, often grow into surrounding tissue and can also...
Umeå, Sweden – A pioneering study at Umeå University, Sweden, has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumour known as glioblastoma. Having identified the factors that glioblastoma uses to respond to neurons by growing and spreading, this discovery paves the way...
MOUNTAIN VIEW, Calif. & BOSTON, Mass. — DNAnexus, Inc., the provider of the Precision Health Data Cloud, and TMA Precision Health, a global health platform for rare diseases, today announced a collaboration to advance basic and translational research for patients who have a rare disease. As part of the agreement,...
Venice, Italy – New research being presented at the European Congress on Obesity (ECO) in Venice, Italy (12-15 May), and published in the International Journal of Obesity, could help explain why type 2 diabetes is more common in men than in women. “Previous studies have shown that men develop type...
CHAPEL HILL, NC — Eating food and absorbing its nutrients is an everyday occurrence, but this normal activity can look different for someone who suffers from inflammatory bowel disease. IBD, which includes Crohn’s disease and ulcerative colitis, can cause chronic inflammation of the digestive tract – which for many reasons...