Cincinnati, Ohio – An international, multisite phase 3 trial co-led by a University of Cincinnati researcher found Parkinson’s disease medication delivered through an infusion pump is safe and effective at reducing symptoms for longer periods of time. These results, published March 15 in the Lancet Neurology journal, could lead to...
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Researchers show that patients with central diabetes insipidus who lack anti-rabphilin-3A antibodies could be at a higher risk of tumor development Toyoake Aichi, Japan – Central diabetes insipidus (CDI), a rare condition involving the destruction or degeneration of neurons of the hypothalamic-posterior pituitary in the brain, has several likely underlying...
ATLANTA – New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, found that JAK inhibitors (JAKi) and tocilizumab elicited better response rates in VEXAS syndrome compared to other targeted therapies. VEXAS syndrome is a rare and often fatal autoimmune condition caused by a mutation in...
New Rochelle, NY – A new study in the peer-reviewed journal Human Gene Therapy showed that more than half of individuals with Niemann-Pick disease, type C1 (NPC1) who were tested lacked neutralizing antibodies against either adeno-associated virus (AAV) 2 or AAV9. Click here to read the article now. NPC1 is a rare, fatal neurodegenerative...
ATLANTA — New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, found that rheumatoid arthritis (RA) patients in sustained remission who stopped TNF inhibitors (TNFi) had significantly more flares and lower Boolean 2.0 remission rates compared with those who continued treatment. Boolean 2.0 is a...
Wilmington, DE – Laser epilation, commonly known as laser hair removal, reduced the risk of recurrence in patients with pilonidal disease, an inflammatory, painful, and sometimes chronic or recurring condition, according to research conducted by Peter C. Minneci, M.D., Chair of Surgery at Nemours Children’s Health, Delaware Valley, and published...
ANN ARBOR, Mich. — At the ends of chromosome are special pieces of DNA called telomeres. Think of it as the little tip that caps off a shoelace. The telomeres send signals to the cells to let them know it’s the end point, not a break that should be repaired....
Wellington, New Zealand – Researchers at the University of Otago’s Department of Paediatrics and Child Health think that the analysis of intronic regions through various methods could uncover novel variants responsible for causing Dravet syndrome (DS), according to a study recently published in Epilepsia Open. “We demonstrate that targeted interrogation of...
Boston, Mass. – A new study, “Timing of Orthostatic Hypotension and its Relationship with Falls in Older Adults”, has brought critical insights into the assessment of orthostatic hypotension, a drop in blood pressure commonly found among older adults when transitioning from a sitting or lying position to a standing position...
MIAMI, FLORIDA – Many people with stage II or III colon cancer receive additional, or adjuvant, chemotherapy following surgery. However, clinical trials have shown that this treatment doesn’t improve the chances of survival for every patient. A study published July 25 in Cell Reports Medicine identifies and validates a 10-gene...