Boston, Massachusetts – The Neuroendocrine Tumor Research Foundation celebrates a significant milestone in cancer therapy: a first-in-human CAR T cell therapy clinical trial for neuroendocrine tumors (NETs) will open in 2024. NETRF supported the early-stage, preclinical research that led to the development of this therapy. Chimeric Therapeutics, an Australian leader...
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Aarhus, Denmark – Researchers have come one step closer to answering why, in some patients, a type of lymphoma changes from indolent to aggressive, and in particular they are closer to identifying which patients are at high risk of this change happening. Part of the answer lies in the protein...
A research in mice has demonstrated how tangles of a so-called tau protein can spread within the brain. Tangled masses of that tau protein contribute to several neurodegenerative diseases – those that destroy brain functions – including Alzheimer’s disease. The research has provided insights into how tau tangles spread that...
HOUSTON, Texas – Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence. The team developed a machine learning system called AI-MARRVEL (AIM) to help prioritize potentially causative variants for Mendelian...
Urbana, Ill. – Supported by a $2 million R01 grant from the National Institutes of Health, the Auerbach Lab at the Beckman Institute for Advanced Science and Technology will examine how different genes associated with autism spectrum disorders may similarly impact our brain’s neurons, resulting in heightened sensitivity to sounds....
Berlin, Germany – When certain connections in the brain do not function correctly, disorders such as Parkinson’s disease, dystonia, obsessive-compulsive disorder (OCD), and Tourette’s syndrome may result. Targeted stimulation of specific areas in the brain can help alleviate symptoms. To pinpoint the exact therapeutic target areas of the brain, a...
Chiba, Japan – Prostate cancer is the second most common cancer among men worldwide, following lung cancer. In the United States alone, nearly 300,000 new cases are diagnosed annually. While reducing testosterone and other male hormones can be an effective treatment for prostate cancer, this approach becomes ineffective once the...
Chiba, Japan – Nasopharyngeal carcinoma (or NPC) is a rare type of cancer affecting the epithelial tissue of the nasopharynx, the upper part of the throat behind the nasal cavity. Among the three main subtypes of NPC, non-keratinizing undifferentiated squamous carcinoma is endemic to the regions of Southern China and...
LOS ANGELES, Calif. — A groundbreaking study led by researchers at Children’s Hospital Los Angeles offers critical insights into Ewing Sarcoma, a rare and aggressive bone and soft tissue cancer that primarily affects children and adolescents. The study, a close collaboration with the Keck School of Medicine of USC, provides...
Cold Spring Harbor, NY – Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes. It may also help cancer spread. How this works has remained a mystery—a challenge for cancer care. Xue-Yan He, a...