LINCOLN, Neb. (KOLN) -The annual Nebraska Football Road Race will return to an in-person format this summer with the family-friendly event set for Father’s Day on Sunday, June 20. The Nebraska Football Road Race presented by the Lincoln Track Club features the one-mile Fun Run set to begin at 8...
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CORNWALL — Ryan Neiswender is as bright, perceptive and articulate as any 15-year-old could be. But for someone so intellectually aware, the soon-to-be Cedar Crest High School freshman appears to be profoundly oblivious to the fact that he’s been dealt a bad hand in life. That’s probably because when Neiswender...
BOSTON, Mass. – The NEJM Evidence has published interim data from the first part of Phase I/II CYPIDES trial evaluating the safety and efficacy of ODM-208 (or MK-5684), an investigational, oral CYP11A1 inhibitor, in heavily pretreated patients with metastatic castration-resistant prostate cancer (mCRPC). Prostate cancer continues to be regulated by...
FOSTER CITY, Calif. — Gilead Sciences, Inc. (Nasdaq: GILD) today announced The New England Journal of Medicine (NEJM) published the full results from the positive Phase 3 ASCENT-04/KEYNOTE-D19 study evaluating the combination of Trodelvy® (sacituzumab govitecan-hziy) plus Keytruda® (pembrolizumab) in first-line PD-L1+ (CPS ≥10) metastatic triple-negative breast cancer (TNBC). ASCENT-04 successfully met its primary...
TARRYTOWN, N.Y. — Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced updated data for their investigational gene therapy DB-OTO for profound genetic hearing loss due to variants of the otoferlin (OTOF) gene were published in The New England Journal of Medicine and presented during an oral presentation at the annual American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNSF) meeting. These latest...
SAN FRANCISCO – Nektar Therapeutics (Nasdaq: NKTR) today announced the publication of preclinical data in the Journal of Translational Autoimmunity describing NKTR-358, a first-in-class, composition of stable PEG conjugates of native IL-2 designed to selectively stimulate T regulatory (Treg) cell function. NKTR-358 is currently in development for the treatment of...
ORLANDO, Fla. — Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could someday serve as an effective cancer therapy, according to a study led by Nemours Children’s Health researchers and published today in Cancer Research Communications, a journal of...
Jacksonville, Florida – Researchers from Nemours Children’s Health will present several studies at the American Society of Hematology (ASH) conference, Dec. 9-12 in San Diego. Nemours Children’s researchers will focus primarily on sickle cell disease (SCD), a group of inherited red blood disorders marked by defective hemoglobin that causes pain...
Bottom Line: Patients with liver cancer who received immune checkpoint inhibitors (ICIs) before surgery—including those who would not have been eligible for surgery by conventional criteria—had similar outcomes to patients who received surgery upfront, according to results from a retrospective study. Journal in Which the Study was Published: Cancer...
Outcomes for melanoma patients have vastly improved thanks to new treatment options. However, those with high-risk disease who have their tumors surgically removed still have a substantial chance of relapse. A team of researchers from institutions across the United States, including Moffitt Cancer Center, launched a phase 2 clinical trial...