Basel, Switzerland – When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets for cancer immunotherapies. Cancer cells function in turbo mode: Their metabolism is programmed for rapid...
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Fukui, Japan – Cancer is a leading cause of death globally. One of the primary reasons why cancer is such a deadly disease is the ability of cancer cells to become drug-resistant. After decades of medical research, scientists came to understand that malignant tumors often harbor a special population of...
Liverpool, England – A new study from the University of Liverpool represents a significant step forward in scientists’ understanding of Alzheimer’s disease. Researchers have shed new light on how mechanical signalling in the brain is disrupted and could lead to the condition which accounts for 60-80% of dementia cases worldwide....
MINNEAPOLIS, Minn. – The Sudan virus, a close relative of Ebola, has a fatality rate of 50% but remains poorly understood in terms of how it infects cells. Currently, no approved treatments exist. To address this critical gap in pandemic preparedness, researchers at the University of Minnesota and the Midwest...
Padua, Italy – A study by the University of Padua, CNR Padua, and the “Mario Negri” Institute in Milan has been published in Molecular Therapy Nucleic Acids under the title “Restoration of myogenesis in ALS-myocytes through miR-26a-5p-mediated Smad4 inhibition and its impact on motor neuron development”. The research paves the way for new...
Turku, Finland – White blood cells, the cells of our immune system, fight against cancer, bacteria, and viruses. However, not all white blood cells destroy cancer cells and some can even promote cancer growth. The most important cell types that destroy cancer cells are cytotoxic T cells and natural killer...
Nashville, Tennessee – Inherited diseases of metabolism and immunity have more in common than previously recognized, according to a new study published in the journal Science Immunology. The findings point to a new set of metabolic genes that are important for the function of immune system T cells, and they...
New York, NY – An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers, according to a new study by scientists at Weill Cornell Medicine. The results could potentially lead to new therapies for patients with limited options and add to the significant...
Washington, D.C.—Legionnaires’ disease (LD), a rare and severe type of pneumonia, is a respiratory infection caused by species of Legionella bacteria. One of the most accurate ways to diagnose LD is to perform culture on samples from a patient’s lower respiratory tract, but those samples are difficult to obtain. In...
New York, NY – Researchers at NYU College of Dentistry and NYU Grossman School of Medicine are closer to understanding what drives the autoimmune disorder Sjögren’s disease, thanks to new discoveries about the role of calcium signaling, regulatory T cells, and interferon. Their latest study, published in Science Translational Medicine,...