HEIDELBERG, Germany – BioMed X and the Universitätsmedizin Mannheim announced today the publication of two manuscripts in the field of cancer immunology in the journal Science Advances. The work is based on a collaboration between both institutions and researchers at the German Cancer Research Center (DKFZ), the University of Heidelberg,...
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Tampere, Finland – A new study conducted by researchers at Tampere University and Tampere University Hospital revealed how aberrant epigenetic regulation contributes to the development of atypical teratoid/rhabdoid (AT/RT) tumours, which are aggressive brain tumours that mainly affect young children. There is an urgent need for more research in this...
Chicago, Ill. – The lab of Yongchao C. Ma, PhD, at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago uncovered a novel mechanism that leads to motor neuron degeneration in spinal muscular atrophy (SMA). This discovery offers a new target for treatment that...
SOUTH BEND, Ind.– Indiana University School of Medicine researchers at the school’s South Bend regional campus, in collaboration with colleagues at the University of Notre Dame, have identified a new therapeutic target for pulmonary hypertension, a type of high blood pressure that affects the blood vessels in the lungs. Their...
Seoul, South Korea – The primary cause of lung cancer is smoking. However, the incidence of lung cancer among never-smokers has been steadily increasing, especially among women. While approximately 80% of never-smoking lung cancer patients are prescribed targeted therapies that focus on mutations in proteins such as EGFR and ALK,...
Sapporo, Japan – Major histocompatibility complex (MHC) class I molecules are an immune complex present on the surface of all cells in humans. MHC class I molecules are a prerequisite for the immune system to recognize and eliminate cancer. When cancer cells are faced with pressure from the immune system,...
A new cognitive test for detecting Alzheimer’s disease is quicker and more accurate than many current tests, and could help diagnose early dementia, concludes a study published on bmj.com today. An estimated 24 million people throughout the world have dementia and the number affected will double every 20 years. Early...
Researchers at the University of British Columbia (UBC) and BC Cancer, in partnership with BC Children’s Hospital Research Institute (BCCHR), have developed a new test to more easily diagnose medulloblastoma, the most common malignant childhood brain tumour. The test — which can distinguish between extremely high-risk medulloblastoma cases that need...
Vienna, Austria – A research team led by Georg Stary (Medical University of Vienna and CeMM) has identified a new approach to treating the inflammatory disease sarcoidosis. In a clinical study, the inhibition of a specific signaling pathway showed clear success in the treatment of granulomas in the skin. This...
Barcelona, Spain – A team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and the Urologic Tumours Unit of the Institut Català d’Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) have found a new therapeutic strategy for patients with a specific subtype of metastatic prostate...