Los Angeles, Calif. – Acute lymphoblastic leukemia (ALL), the most common childhood cancer, especially affects children of Hispanic/Latino origin in the United States. They are 30-40% more likely to get ALL than non-Hispanic white children, but the exact genetic basis and cause of that increased risk are unknown. Now, a...
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Researchers at the Keck School of Medicine of the University of Southern California (USC) have identified a key mechanism that causes chromosomes within blood cells to break—an occurrence that marks the first step in the development of human lymphoma. The study provides researchers with the clearest insight yet into why...
Los Angeles, Calif. – The California Institute for Regenerative Medicine has awarded a $6 million grant to USC investigators pioneering a new first-of-its-kind genetic therapy for glioblastoma, a severe form of brain cancer. The treatment would be the first gene therapy for glioblastoma to use a novel, more precise delivery...
Los Angeles, Calif. – In an innovative new study of glioblastoma, scientists used artificial intelligence (AI) to reprogram cancer cells, converting them into dendritic cells (DCs), which can identify cancer cells and direct other immune cells to kill them. Glioblastoma is the most common brain cancer in adults and also...
Philadelphia, Pennsylvania – In the retinas of human eyes, the cones are photoreceptor cells responsible for color vision, daylight vision, and the perception of small details. As vision scientists from the Division of Experimental Retinal Therapies at the University of Pennsylvania School of Veterinary Medicine, Gustavo D. Aguirre and William A. Beltran have been working for...
Hong Kong – A crucial player in genomic integrity maintenance, DNA Polymerase Theta (Polθ) provides a potential synthetic lethal relationship in BRCA-deficient tumors, which are particularly prevalent in certain tumor types including triple-negative breast cancers (TNBC) and ovarian cancers. In fact, BRCA-deficient tumors account for 11-16% of TNBC cases, and...
SAN ANTONIO, TX – A drug developed at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has been shown to extend survival for patients with glioblastoma, the most common primary brain tumor in adults. Results of a trial led by the university revealed that...
SAN ANTONIO, TX – Research led by in part by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) finds that the most common cerebral small-vessel disease feature seen in brain magnetic resonance imaging is a primary vascular factor associated with dementia risk. Results of...
SAN ANTONIO, Texas – Researchers at the University of Texas Health Science Center at San Antonio have discovered a way to delay or even block recurrence of the deadliest brain cancer after radiation, bringing new hope for survival. Ironically, the scientists found that the customary treatment for glioblastoma, ionizing radiation,...
Dallas, Texas – UT Southwestern Medical Center researchers have identified a genetic mutation that slows the growth of melanoma and potentially other cancers by harnessing the power of the immune system. Their findings, published in the Journal of Experimental Medicine, could lead to new treatments that improve outcomes from existing...