Ottawa, Canada – A team from the University of Ottawa’s Faculty of Medicine has completed an exciting new study that reveals the inner workings of gene mutations that result in an ultra-rare syndrome with fewer than 100 reported cases since its first description in the early 1960s. The hard-won research...
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Philadelphia, PA – Researchers from the University of Pennsylvania, Perelman School of Medicine, Gene Therapy Program, and Moderna, have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum leucine levels in a mouse model of maple syrup urine disease (MSUD). Click here to read...
PHILADELPHIA, PA – When cells in the human body divide, they must first make accurate copies of their DNA. The DNA replication exercise is one of the most important processes in all living organisms and is fraught with risks of mutation, which can lead to cell death or cancer. Now,...
Brisbane, Australia – University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited. Dr Anne Hahn and Associate Professor Steven Zuryn from UQ’s Queensland Brain Institute said the findings could provide a promising therapeutic avenue to stop the onset of heritable and age-related...
Brisbane, Australia – University of Queensland researchers have identified an opportunity to reduce infections in people living with cystic fibrosis. Professor Matt Sweet, Dr Kaustav Das Gupta and Dr James Curson from UQ’s Institute for Molecular Bioscience have discovered a fault in the bacteria-killing function of immune cells in people...
Rochester, New York – Standard chemotherapy regimens, which are mostly based on testing in relatively young and healthy patients, may do more harm to older adults with cancer who often struggle with other health issues. New research, published yesterday in JAMA Network Open, shows that lowering the dose and adjusting...
Sheffield, England – Researchers at the University of Sheffield have discovered how a hospital superbug Clostridioides difficile (C.diff) can rapidly evolve resistance to vancomycin, the frontline drug used in the UK. Clostridioides difficile (C. diff), a type of bacteria which often affects people who have taken antibiotics, is responsible for approximately...
Los Angeles, CA – Cycles of a diet that mimics fasting can reduce signs of immune system aging, as well as insulin resistance and liver fat in humans, resulting in a lower biological age, according to a new USC Leonard Davis School of Gerontology-led study. The study, which appears in...
Odens, Denmark – Cancer cells are characterized by their aggressiveness: they grow rapidly and spread to other parts of the body. To enable this, numerous mechanisms come into play, and one of them involves a protein called MYC, which activates certain genes on the cancer cell’s DNA strand, causing the...
AUSTIN, Texas — Better prevention of Type 2 diabetes could save both lives and money. The U.S. spends over $730 billion a year — nearly a third of all health care spending — on treating preventable diseases like diabetes. For the 98 million adults who are prediabetic and at risk of developing...