research News

Ann Arbor, Mich. – Blood clots and pregnancy loss are commonly recognized features of antiphospholipid syndrome, but thrombocytopenia is the third most prevalent symptom, impacting up to half of antiphospholipid syndrome patients. Thrombocytopenia is characterized by lower than normal platelets in the blood. Platelets are small cell fragments that play...
Seattle, Washington – Prostate cancer stands as a prevalent threat to men’s health, ranking second in cancer-related deaths in the United States. Each year, approximately 250,000 men in the U.S. receive a prostate cancer diagnosis. While most cases have low morbidity and mortality rates, a subset of cases demands aggressive...
Plymouth, England – Scientists have developed a potentially transformative new technique that could aid in the discovery and development of new therapeutics for a number of globally prevalent autoimmune diseases. Conditions such as lupus, rheumatoid arthritis and inflammatory bowel disease (IBD) – as well as failures within transplanted cells –...
Your immune system plays an important function in your health — it protects you against viruses, bacteria, and other toxins that can cause disease. In autoinflammatory diseases, however, the immune system goes awry, causing unprovoked and dangerous inflammation. Now, researchers from the National Institute of Arthritis and Musculoskeletal and Skin...
Sacramento, CA – Researchers at UC Davis Comprehensive Cancer Center have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice. Silencing the galectin 1 (Gal1) protein, which is often over-expressed in HCC, also improved the anti-cancer immune response and increased the number of killer T cells inside tumors....
CHAPEL HILL, N.C. – Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that variants in the SPTBN1 gene can alter neuronal architecture, dramatically affecting their function and leading to a rare, newly defined neurodevelopmental syndrome in children. Damaris Lorenzo, PhD, assistant...
Memphis, TN – A collaboration between scientists from St. Jude Children’s Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma (ALCL), an aggressive form of cancer. These proteins comprise a core regulatory circuit (CRC) that surprisingly incorporates a dysregulated signaling protein....