Zürich, Switzerland – Sjögren’s disease is rare in children, and presenting symptoms differ from those seen in adults. For example, paediatric patients present less often with sicca complaints, and more frequently with parotid gland swelling and fever.1 This new work aimed to identify potentially dysregulated molecular pathways in children with...
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PORTLAND, Ore. and MUMBAI, India — A clinical study to validate the beta thalassemia (beta-thal) diagnostic capability of the Gazelle™ Hb Variant Test from Hemex Health, published in the journal Biosensors, showed that Gazelle correctly identified participating subjects with beta-thal major, beta-thal intermedia, and beta-thal trait with a combined accuracy...
Stockholm, Sweden – Type 2 diabetes and prediabetes are associated with accelerated brain ageing, according to a new study from Karolinska Institutet in Sweden published in the journal Diabetes Care. The good news is that this may be counteracted by a healthy lifestyle. Type 2 diabetes is a known risk...
St. Louis, Missouri – An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice. The study, from researchers at Washington University School...
LOS ANGELES, CA – UCLA researchers uncover new details about how the immune system can recognize and kill cancer cells, unlocking potential new strategies to treat aggressive cancers FINDINGS Researchers at the UCLA Jonsson Comprehensive Cancer Center have found certain immune cells can still fight cancer even when the cancer cells...
São Paulo, Brazil – CD4+ T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections. However, an article published in the journal Cell Reports shows that an imbalance in the volumes of these defense cells in different parts of the lung in response...
ATLANTA – New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, shows that ultrasound-detected salivary gland abnormalities in primary Sjögren’s become more severe over time and that the slow-to-progress disease likely starts long before it is first detected. Sjögren’s disease also known as Primary Sjögren’s...
ATLANTA — New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, shows that patients with refractory juvenile systemic sclerosis improved significantly on nearly all measures for two years following autologous stem cell transplant. Juvenile-onset systemic sclerosis (jSSc), also called scleroderma, is a disfiguring autoimmune disorder...
São Paulo, Brazil – A single-dose dengue vaccine produced by Butantan Institute in São Paulo state (Brazil) prevents development of the disease in 79.6% of those vaccinated, according to an article published today in The New England Journal of Medicine. Called Butantan-DV, the vaccine contains attenuated versions of all four...
Baltimore, Maryland – Comparing PET scans of more than 90 adults with and without mild cognitive impairment (MCI), Johns Hopkins Medicine researchers say relatively lower levels of the so-called “happiness” chemical, serotonin, in parts of the brain of those with MCI may play a role in memory problems including Alzheimer’s...