San Diego, Calif. – An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study from the University of California San Diego. The treatment, composed of nanoparticles fashioned from the cowpea mosaic virus—a virus that infects...
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Los Angeles, Calif. – A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington’s disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new...
Basel, Switzerland – When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets for cancer immunotherapies. Cancer cells function in turbo mode: Their metabolism is programmed for rapid...
Fukui, Japan – Cancer is a leading cause of death globally. One of the primary reasons why cancer is such a deadly disease is the ability of cancer cells to become drug-resistant. After decades of medical research, scientists came to understand that malignant tumors often harbor a special population of...
Liverpool, England – A new study from the University of Liverpool represents a significant step forward in scientists’ understanding of Alzheimer’s disease. Researchers have shed new light on how mechanical signalling in the brain is disrupted and could lead to the condition which accounts for 60-80% of dementia cases worldwide....
MINNEAPOLIS, Minn. – The Sudan virus, a close relative of Ebola, has a fatality rate of 50% but remains poorly understood in terms of how it infects cells. Currently, no approved treatments exist. To address this critical gap in pandemic preparedness, researchers at the University of Minnesota and the Midwest...
Padua, Italy – A study by the University of Padua, CNR Padua, and the “Mario Negri” Institute in Milan has been published in Molecular Therapy Nucleic Acids under the title “Restoration of myogenesis in ALS-myocytes through miR-26a-5p-mediated Smad4 inhibition and its impact on motor neuron development”. The research paves the way for new...
Turku, Finland – White blood cells, the cells of our immune system, fight against cancer, bacteria, and viruses. However, not all white blood cells destroy cancer cells and some can even promote cancer growth. The most important cell types that destroy cancer cells are cytotoxic T cells and natural killer...
Nashville, Tennessee – Inherited diseases of metabolism and immunity have more in common than previously recognized, according to a new study published in the journal Science Immunology. The findings point to a new set of metabolic genes that are important for the function of immune system T cells, and they...
New York, NY – An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers, according to a new study by scientists at Weill Cornell Medicine. The results could potentially lead to new therapies for patients with limited options and add to the significant...