Göttingen, Germany – In the journal “Science Translational Medicine”, scientists from DZNE and LMU Hospital report on new insights into the mechanisms of “Niemann-Pick type C” (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood. Their findings, based on studies in mice, cell cultures...
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PLYMOUTH MEETING, Pennsylvania — The National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers—today published its first ever set of treatment recommendations pertaining to neuroblastoma. Neuroblastoma is a type of solid tumor cancer that typically occurs in early childhood, with the majority diagnosed before age five. Neuroblastoma is the...
RIVERSIDE, Calif. — Imagine if we could inhale scents that delay the onset of cancer, inflammation, or neurodegenerative disease. Researchers at the University of California, Riverside, are poised to bring this futuristic technology closer to reality. In lab experiments, a team led by Anandasankar Ray, a professor of molecular, cell and systems...
Boston, Mass. – Sickle cell disease, while rare, is the most common inherited blood disorder and affects over 100,000 people in the United States, more than 90% of whom are Black according to the Centers for Disease Control and Prevention. Although a medication called hydroxyurea can alleviate pain and lower...
LOS ANGELES, Calif. — A clinical trial from Keck Medicine of USC aims to provide a surgical solution for patients with a form of advanced pancreatic cancer previously considered inoperable. The study will investigate if chemotherapy followed by a novel type of surgery to remove the cancer is a safe...
London, Ontario – A new study shows oxygenation levels in the placenta, formed during the last three months of fetal development, are an important predictor of cortical growth (development of the outermost layer of the brain or cerebral cortex) and is likely a predictor of childhood cognition and behaviour. “Many...
Lausanne, Switzerland – Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a negative role in cancer immunity – is positively correlated with long-term cancer remission....
Boston, MA – A significant survival improvement for adults with newly diagnosed BCR::ABL1-negative B-cell precursor acute lymphoblastic leukemia is published today by the New England Journal of Medicine. The practice-changing finding is from the randomized phase 3 study E1910 (NCT02003222), which evaluated blinatumomab immunotherapy in patients who were in remission...
London – The effectiveness of live zoster (shingles) vaccine is highest in the first year after vaccination and then wanes substantially. But it continues to provide some protection against shingles and its complications ten years after vaccination, even in patients with a weakened immune system, finds a study published by...
ST. PAUL, Minn. — One in four multiple sclerosis (MS) patients are declining to fill their prescriptions likely due to high out-of-pocket costs, according to new research conducted by pharmacy benefits manager Prime Therapeutics (Prime). The study found that patients with an out-of-pocket expense greater than $250 were seven times...