FOSTER CITY, Calif. — Mirum Pharmaceuticals, Inc., today announced top-line results of the Phase 2 EMBARK study evaluating LIVMARLI® (maralixibat) oral solution versus placebo given as an adjuvant therapy to Kasai surgery in patients with biliary atresia. The study did not meet its primary endpoint of mean change in bilirubin...
research News
SOUTH SAN FRANCISCO, Calif. — Mission Bio, a leader in single-cell multi-omics solutions for precision medicine, announced a new publication led by Hervé Avet-Loiseau, MD, PhD, revealing new insights into disease progression of multiple myeloma (MM). Using Mission Bio’s single-cell DNA sequencing Tapestri® Platform, the study shows that solely targeting...
CAMBRIDGE, MA — When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient’s body surface area. This is estimated by plugging the patient’s height and weight into an equation, dating to 1916, that was formulated from data on just nine patients. This simplistic dosing...
CAMBRIDGE, MA — Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating — a condition commonly known as “chemo brain.” MIT researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating chemo brain. In a study...
Cambridge, Mass. – Patients with late-stage cancer often have to endure multiple rounds of different types of treatment, which can cause unwanted side effects and may not always help. In hopes of expanding the treatment options for those patients, MIT researchers have designed tiny particles that can be implanted at...
CAMBRIDGE, MA — For most patients, it’s unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death. Studies have identified certain genes that confer a higher risk of the disease, but scientists believe there are...
Cambridge, Mass. – A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain’s 40Hz “gamma” frequency rhythms could treat Alzheimer’s disease in mice, a growing evidence base supporting the idea that it can improve brain health—in humans...
Singapore – A group of researchers, led by Nanyang Technological University, Singapore (NTU Singapore), has developed a mobile application to educate individuals living with diabetes and their caregivers with knowledge of the disease and assist them in monitoring their day-to-day activities, which includes medication, physical activity, and their diet. The...
Gothenburg, Sweden – A moderate low-carbohydrate diet for adults with type 1 diabetes has advantages over traditional diet. The average blood sugar level is reduced and the time with good values during a 24 hour period is increased, without any negative health impact. This has been shown in a study...
Moderna hopes to offer a new set of life-saving vaccines targeting cancer, heart disease and other conditions by 2030, a spokesperson for the company told CNBC on Monday. The spokesperson confirmed remarks Moderna’s chief medical officer, Dr. Paul Burton, made to the Guardian on Saturday. Burton said he’s confident those...