Scientists have found success in treating a ‘neglected’ inflammatory condition, polymyalgia rheumatica, with a drug that could provide an alternative to steroids for patients. The study, carried out by Anglia Ruskin University (ARU) and published in the New England Journal of Medicine, describes a successful trial of sarilumab. The drug,...
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Amsterdam – After 40 years of treating metastatic bladder cancer with chemotherapy as a primary treatment, scientists now present a new approach using immunotherapy combinations. The results of not just one, but two studies have been presented at the European Society for Medical Oncology (ESMO) conference in Madrid. The outcomes...
Norwich, England – Researchers have been able to identify at least three distinct subtypes of a rare type of bone cancer for the first time, which could transform clinical trials and patient care.While genetic sequencing has previously helped to uncover different subtypes of other cancers, like breast or skin cancer,...
Toronto, Canada – Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation treatments for medulloblastoma, the most common malignant brain tumour in children.Within cancerous tumours, there are special cells, called tumour-propagating cells, that drive tumour formation and growth. Since these cells...
BOSTON, Mass. — Brain disorders like Parkinson’s (PD) or Alzheimer’s Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at...
Bergen, Norway – University of Bergen researcher Markus Miettinen is among the first scientists to provide a detailed description of protein clumps associated with Huntington’s disease. The findings, which could pave the way for new diagnostic tools and treatments, were recently presented in an article in Nature Communications. “There is...
Beijing, China – Imagine the deep frustration of countless men who long to become fathers, only to face infertility due to a genetic condition they can’t control. For those with Klinefelter syndrome, this painful reality is a constant struggle. How does an extra X chromosome lead to infertility in men? Professor...
Chicago, Illinois – Immunotherapy before surgery for patients with metastatic melanoma appears to be especially successful. Fifty-nine percent of patients responds so well to this therapy that adjuvant treatment is no longer needed, according to the results of the NADINA study that were published today. The NADINA study, led by...
Hinxton, England – Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people and their families as treatment can require surgery...
San Francisco, Calif. – Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed. But now, UC San Francisco researchers have found a way to identify the condition while patients are still alive. A study appearing in Neurology on...