CAMBRIDGE, MA — One of the immune system’s primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance and develop into more advanced tumors. A new study from MIT and Dana-Farber Cancer Institute has identified one strategy...
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Bethesda, Maryland – The drug minocycline, an antibiotic that also decreases inflammation, failed to slow vision loss or expansion of geographic atrophy in people with dry age-related macular degeneration (AMD), according to a phase II clinical study at the National Eye Institute (NEI), part of the National Institutes of Health....
Ann Arbor, Mich. – Participation in recreational activities — including golfing, gardening or yard work, woodworking and hunting — may be associated with an increase in a person’s risk for developing amyotrophic lateral sclerosis, or ALS, a Michigan Medicine study finds. While many activities were associated with increased ALS risk,...
TAMPA, Fla. — Penile squamous cell carcinoma is a rare malignancy with limited treatment options and poor prognosis, especially in advanced stages. Because of its rarity, few studies focus on better understanding and managing this disease. In a new article published in the Journal of the National Cancer Institute, Moffitt...
BURTON, Ohio — The first signs that something was wrong with 11-year-old Connor Teare came when he was a toddler. His muscles were growing increasingly rigid and becoming more difficult to move. He went from leg braces to a walker and, finally, a wheelchair by the time he was 5....
New York, NY – A novel treatment for polycythemia vera, a potentially fatal blood cancer, demonstrated the ability to control overproduction of red blood cells, the hallmark of this malignancy and many of its debilitating symptoms in a multi-center clinical trial led by the Icahn School of Medicine at Mount...
WASHINGTON, DC — In a first-of-its-kind clinical trial, researchers found that intravenous therapies made from virus-specific T-cells (VST) can effectively treat immunocompromised pediatric patients, far surpassing the current standard of care, according to new research published in Nature Communications. More than 60% of patients in the phase 2 clinical trial...
Cleveland, Ohio – Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options. Conducted as part of the multicenter RUBY Trial, researchers shared data on the safety and effectiveness of renizgamglogene autogedtemcel...
Cincinnati, Ohio – A multidisciplinary team of University of Cincinnati Cancer Center researchers have opened a Phase 2 clinical trial to test a new combination treatment for glioblastomas (GBM), the most deadly form of brain tumors. The team, led by UC’s Pankaj Desai, PhD, and Trisha Wise-Draper, MD, PhD, has...
Helsinki, Finland – A multidisciplinary team of scientists led by University of Helsinki report that a progressive neurodegenerative disease can be triggered by a viral infection. The mechanism relates to mitochondrial roles in antiviral defense mechanisms. The scientists report that a specific gene variant affecting the mitochondria disturb cellular antiviral...