SAN FRANCISCO, Calif. — Gordian Biotechnology, an in vivo drug discovery and development company, today announced its platform that enables patient predictive, in vivo screening of hundreds of gene targets for FDA-recognized diseases of aging at a scale never before possible. The company has raised $60 million to date from...
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Shanghai, China – This study is led by Prof. Wei-Li Zhao (Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine). G-protein coupled receptors (G-protein ) are critical targets for viral...
MENLO PARK, Calif. — Grace Science, LLC announced today that the first patient was dosed in an open-label Phase 1/2/3 clinical trial of GS-100, an AAV9 gene replacement therapy for the treatment of NGLY1 Deficiency. Part 1/2 of the study will investigate dose-escalation and the safety and efficacy of a single...
PHILADELPHIA – According to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research, men with prostate cancer who consumed the active compounds in green tea demonstrated a significant reduction in serum markers predictive of prostate cancer progression. “The investigational agent used...
However, a new study may have found a new treatment that can help the sickest sarcoma patients. “We have learned that sarcoma patients whose cancer cells have a high expression of the cep135 protein are worse off. But inhibiting a gene called plk1 also inhibits growth of the sarcoma cells,...
Brussels, Belgium – During the surgery Wednesday April 17, the Da Vinci Xi surgical system was combined with MMI’s Symani surgical system. In collaboration with abdominal surgeon Dr Martijn Schoneveld, the plastic and reconstructive surgery team performed a fully robotic lymph node transplant, overseen by Professor Moustapha Hamdi, Head of...
San Francisco, Calif. – A clinical trial that will test three drugs concurrently, and could include more, represents new hope for patients with progressive supranuclear palsy (PSP), an incurable neurodegenerative disorder that usually kills within seven years after symptoms start. Researchers hope the trial, which will be led by UC...
LONG BEACH, Calif. — As reported in today’s issue of the journal Metabolites, researchers at Metabolomycs, a California-based biotechnology company, for the first time applied targeted mass spectrometry to show that pancreatic cancer arises through changes in cellular metabolism and that these changes can be measured with a simple blood...
Tokyo, Japan – Alternative splicing, a process where a single gene can give rise to multiple different proteins via inclusion or exclusion of certain segments of the gene sequence, is known to occur in over 90% of human genes. This leads to the production of numerous transcript isoforms (splice variants...
Tianjin, China – A transformative study has provided a profound understanding of glioblastoma’s molecular subtypes, revealing the nuances of cellular heterogeneity and the mechanisms behind resistance to treatment. This critical research not only enhances our comprehension of this aggressive cancer but also opens new frontiers for the precision-targeting of therapies,...